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1.发明公开
公开(公告)号：EP1755403A1
公开(公告)日：2007-02-28
申请号：EP05745538.8
申请日：2005-05-09
发明人： LOOIJESTEIJN, Petronella, Johanna , ALKEMA, Audrey , VAN HEKEZEN, Maria, Adriana , SIKKEMA, Jan , NAUTA, Arjen
IPC分类号： A23C9/123 , A23C19/032
CPC分类号： A23C9/1236 , A23C9/1234 , A23C19/0323
摘要： The present invention relates to the preparation of a dairy product that has at least one characteristic like or similar to a characteristic of a mixture of at least two dairy products. In a preferred embodiment the dairy product has the taste and preferably also the mouthfeel of a mixture of yoghurt and quark.
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公开(公告)号：EP1649024A2
公开(公告)日：2006-04-26
申请号：EP04774814.0
申请日：2004-07-02
发明人： DEN HENGST, Christiaan, Daniel , GAJIC, Olivera , KUIPERS, Oscar, Paul , KOK, Jan , SIKKEMA, Jan , GEURTS, Johannes, Marie, Wilhelmus , NAUTA, Arjen
CPC分类号： C12N15/746 , A23C9/12 , A23C19/032 , A23C2220/202
摘要： The invention relates to the field of biochemistry, molecular biology and food production. More in particular, the invention relates to methods and means for regulating gene expression. Even more in particular, the invention relates to CodY target sequences. Herein we show that CodY represses its target genes by binding to specific DNA sequences upstream of the respective genes. A conserved target site was identified by analyzing upstream sequences of derepressed genes in a delta codY L. lactis MG1363 derivative, as identified in a DNA micro-array study. The present application furthermore discloses CodY target sequences from other gram-positive bacteria, like B. subtilis and Streptococcus. Hence, the invention provides CodY target sequences that may be used in different applications to repress or derepress gene expression.
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公开(公告)号：EP1196041A2
公开(公告)日：2002-04-17
申请号：EP00946532.9
申请日：2000-07-06
CPC分类号： A23C19/11 , A23C9/1585 , C07K14/33
摘要： Bacteriocins produced by 'food-grade' lactic acid bacteria (LAB) are successfully used as food preservatives. However, they are often characterised by a narrow inhibitory spectrum, acting mainly on closely related bacteria. In order to specifically prevent the growth of spoilage Clostridia, we set out to isolate bacteriocins from closely related Clostridium spp. The cognate genes are cloned and introduced in a starter or non-starter (adjunct) LAB, to be used in cheese manufacturing. The bacteriocins can also be used in the preparation of a pharmaceutical formulation.
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公开(公告)号：EP1196041B1
公开(公告)日：2012-09-12
申请号：EP00946532.9
申请日：2000-07-06
CPC分类号： A23C19/11 , A23C9/1585 , C07K14/33
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公开(公告)号：EP1649024B1
公开(公告)日：2010-03-24
申请号：EP04774814.0
申请日：2004-07-02
发明人： DEN HENGST, Christiaan, Daniël , GAJIC, Olivera , KUIPERS, Oscar, Paul , KOK, Jan , SIKKEMA, Jan , GEURTS, Johannes, Marie, Wilhelmus , NAUTA, Arjen
CPC分类号： C12N15/746 , A23C9/12 , A23C19/032 , A23C2220/202
摘要： The invention relates to the field of biochemistry, molecular biology and food production. More in particular, the invention relates to methods and means for regulating gene expression. Even more in particular, the invention relates to CodY target sequences. Herein we show that CodY represses its target genes by binding to specific DNA sequences upstream of the respective genes. A conserved target site was identified by analyzing upstream sequences of derepressed genes in a delta codY L. lactis MG1363 derivative, as identified in a DNA micro-array study. The present application furthermore discloses CodY target sequences from other gram-positive bacteria, like B. subtilis and Streptococcus. Hence, the invention provides CodY target sequences that may be used in different applications to repress or derepress gene expression.
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