Method for measuring low density lipoprotein cholesterol
    1.
    发明公开
    Method for measuring low density lipoprotein cholesterol 有权
    Verfahren zur Messung von Lipoproteinchollesterol mit geringer Dichte

    公开(公告)号:EP2360480A1

    公开(公告)日:2011-08-24

    申请号:EP11155153.7

    申请日:2011-02-21

    IPC分类号: G01N33/92

    摘要: It is an object of the present invention to provide a method capable of measuring low density lipoprotein cholesterol (LDL) in a body fluid with high selectivity. The present invention provides a method for measuring low density lipoprotein cholesterol (LDL-C) in a body fluid, which comprises treating the body fluid with a polymer compound having an allylamine or diallylamine unit, and measuring the low density lipoprotein cholesterol (LDL-C) using (a) cholesterol esterase and (b) cholesterol oxidase or cholesterol dehydrogenase.

    摘要翻译: 本发明的目的是提供一种能够以高选择性测量体液中的低密度脂蛋白胆固醇(LDL)的方法。 本发明提供一种测定体液中的低密度脂蛋白胆固醇(LDL-C)的方法,其包括用具有烯丙胺或二烯丙基胺单元的高分子化合物处理体液,并测定低密度脂蛋白胆固醇(LDL-C )使用(a)胆固醇酯酶和(b)胆固醇氧化酶或胆固醇脱氢酶。

    Dry analytical element for measurement of high density lipoprotein cholesterol
    5.
    发明公开
    Dry analytical element for measurement of high density lipoprotein cholesterol 有权
    Trockenes分析元素zur Messung von hochdichtem Lipoproteincholesterin

    公开(公告)号:EP2108961A1

    公开(公告)日:2009-10-14

    申请号:EP09005263.0

    申请日:2009-04-09

    IPC分类号: G01N33/92 G01N33/52 C12Q1/60

    CPC分类号: G01N33/92 G01N33/525

    摘要: It is an object of the present invention to provide a dry analytical element for the measurement of HDL-C, in which the interference of lipoproteins other than HDL is suppressed. The present invention provides a dry analytical element for the measurement of a high density lipoprotein cholesterol, which has at least one layer comprising an nonionic surfactant of 3 to 22 g/m 2 , a buffer of 0.1 to 40 mmol/m 2 , dextran sulfate with a molecular weight of 36,000 to 50,000, a divalent metal ion and reagents for measuring high density lipoprotein cholesterol, on a support.

    摘要翻译: 本发明的目的是提供一种用于测量HDL-C的干燥分析元件,其中抑制除HDL之外的脂蛋白的干扰。 本发明提供了一种用于测量高密度脂蛋白胆固醇的干燥分析元件,其具有至少一层,其包含3至22g / m 2的非离子表面活性剂,0.1至40mmol / m 2的缓冲液,硫酸葡聚糖 分子量为36,000至50,000,二价金属离子和用于测量高密度脂蛋白胆固醇的试剂。

    Method for measuring high-density lipoprotein cholesterol
    7.
    发明公开
    Method for measuring high-density lipoprotein cholesterol 有权
    维生素Zur Messung von hochdichtem Lipoproteinchollesterol

    公开(公告)号:EP2065708A1

    公开(公告)日:2009-06-03

    申请号:EP08020603.0

    申请日:2008-11-27

    IPC分类号: G01N33/92

    CPC分类号: G01N33/92 C07C43/23

    摘要: A method for conveniently and quickly measuring high-density lipoprotein cholesterol (HDL-C) in a body fluid sample such as blood, which uses a polycyclic polyglycidol compound, for example, a polyglycidol compound represented by the following general formula (1):

    wherein L represents a C 1 -C 5 alkylene group, R represents an aryl group, m represents an integer of 1 to 5, and n represents an integer of 3 to 20, as a high-density lipoprotein selective surfactant.

    摘要翻译: 一种方便快速地测定体液样品如血液中的高密度脂蛋白胆固醇(HDL-C)的方法,其使用多环聚缩水甘油化合物,例如由以下通式(1)表示的聚缩水甘油化合物:其中 作为高密度脂蛋白选择性表面活性剂,L表示C 1 -C 5亚烷基,R表示芳基,m表示1〜5的整数,n表示3〜20的整数。

    Dry analytical element capable of reducing influence of hemolysis for body fluid component measurement
    9.
    发明公开
    Dry analytical element capable of reducing influence of hemolysis for body fluid component measurement 有权
    具有减少用于测量体液成分在溶血的影响能力的干式分析元件

    公开(公告)号:EP2105739A1

    公开(公告)日:2009-09-30

    申请号:EP09004383.7

    申请日:2009-03-26

    发明人: Inomata, Hiroko

    IPC分类号: G01N33/52 G01N33/53

    CPC分类号: G01N33/521 C12Q1/28

    摘要: It is an object of the present invention to reduce influence of hemolysis in a dry analytical element used for measurement of components in a body fluid sample such as blood. The present invention provides a method for producing a dry analytical element for body fluid component measurement comprising at least a reagent layer containing an H 2 O 2 color developing reagent and a spreading layer provided on the reagent layer, which comprises steps of providing a spreading layer substrate on the reagent layer containing an H 2 O 2 color developing reagent and preparing a spreading layer by coating a low-viscosity solution containing oxidase to the spreading layer substrate and then coating a high-viscosity solution containing other reagent components than oxidase thereto.

    摘要翻译: 这是本发明的一个目的是减少在用于体液样品中成分的测量干式分析元件的溶血的影响:如血液。 本发明提供所提供的试剂层,其包括提供一扩散层的步骤对用于制造体液成分测定,其包括至少一个试剂层含H 2 O 2显色试剂的干式分析元件的方法和扩展层 所述试剂层含H于基板2 O 2显色剂和通过涂布低粘度溶液,其中含有氧化酶的扩散层的基材制备扩散层,然后涂覆高粘度的溶液,其中含有比氧化酶于此其他试剂成分。