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11 条记录 (耗时 0.011 秒)

    New starting compounds for the preparation of cephem compounds and processes for preparation thereof
    4.
    发明公开
    New starting compounds for the preparation of cephem compounds and processes for preparation thereof 失效
    Ausgangsverbindungenfürdie Herstellung von Cephalosporinderivaten und Verfahren zu deren Herstellung。

    公开(公告)号：EP0156118A1

    公开(公告)日：1985-10-02

    申请号：EP85100916.7

    申请日：1981-08-25

    申请人： FUJISAWA PHARMACEUTICAL CO., LTD.

    发明人： Kamiya, Takashi ,  Teraji, Tsutomu ,  Nakai, Yoshiharu ,  Sakane, Kazuo ,  Goto, Jiro

    IPC分类号： C07D239/42 ,  C07D213/73 ,  C07D213/75 ,  A61K31/545 ,  C07D501/46

    CPC分类号： C07D213/75 ,  C07D239/42

    摘要： A compound of the formula:
    wherein R 1 is amino or a protected amino group,

    X is N or CH, and
    R 5 is ethyl, cyclo (lower) alkyl, cyclo (lower) alkenyl, lower alkyl having a protected carboxy group, lower alkynyl or lower alkylthio(lower)alkyl,
    provided that X is N when R 5 is lower alkynyl and
    R' is amino when R 5 is ethyl, or a salt therof, and processes fortheir preparation. The compounds are useful as starting material for the preparation of pharmaceutically active cephem compounds.

    摘要翻译： 下式的化合物，其中R 1为氨基或被保护的氨基，X为N或CH，R 5为乙基，环（低级）烷基，环（低级）烯基，低级烷基 具有保护的羧基，低级炔基或低级烷硫基（低级）烷基，条件是当R 5为低级炔基时X为N，当R 5为乙基时，R 1为氨基，或者为盐，和 其准备过程。 该化合物可用作制备药物活性头孢烯化合物的起始原料。

    2-Lower alkyl-7-substituted-2 or 3-cephem-4-carboxylic acid compounds, processes for their preparation and pharmaceutical compositions containing them
    7.
    发明公开
    2-Lower alkyl-7-substituted-2 or 3-cephem-4-carboxylic acid compounds, processes for their preparation and pharmaceutical compositions containing them 失效
    2 - 低级烷基-7-取代的-2-或3-头孢烯-4-羧酸，其制备方法和含有它们的药物组合物的过程。

    公开(公告)号：EP0008442A2

    公开(公告)日：1980-03-05

    申请号：EP79102989.5

    申请日：1979-08-16

    申请人： FUJISAWA PHARMACEUTICAL CO., LTD.

    发明人： Kamiya, Takashi ,  Takaya, Takao

    IPC分类号： C07D501/14 ,  A61K31/545

    CPC分类号： C07D277/587

    摘要： A compound of the formula:


    wherein R 1 is lower alkyl,
    R 2 is carboxy or a protected carboxy group,
    R 3 is amino or a protected amino group and
    R 4 is lower alkyl having halogen atom(s) or lower unsaturated aliphatic group,

    and pharmaceutically acceptable salt thereof, and process for their preparation.
    The invention also relates to the starting derivatives and their preparation and to a pharmaceutical composition comprising, as an effective ingredient, the above compound in association with a pharmaceutically acceptable, substantially non-toxic carrier or excipient, and to a method for treating an infectious disease caused by pathogenes, which comprises administering the above compound to infected human beings or animals.