公开(公告)号：EP3919052A1

公开(公告)日：2021-12-08

申请号：EP20739000.6

申请日：2020-01-09

Applicant: Fuso Pharmaceutical Industries, Ltd.

Inventor： SHINTO, Saki ,  ISHIDA, Minato ,  YAMAMOTO, Keiichi ,  YAMADA, Ken-ichi

IPC: A61K31/137 ,  A61K31/403 ,  A61K31/407 ,  A61K31/47 ,  A61P27/02 ,  A61K9/06 ,  A61K9/08 ,  A61K9/20

Abstract: The present invention provides a pharmaceutical composition for intraocular administration or oral administration, for preventing or treating a retinal disease (such as age-related macular degeneration), or suppressing a progression of the disease in a subject in need of treatment, the composition comprising an effective amount of one or more compounds selected from the following group, and a pharmaceutically acceptable carrier; and a method threfor, a group consisting of apomorphine, eseroline, ethoxyquin, methyldopa, olanzapine and indapamide.

公开(公告)号：EP3650860A1

公开(公告)日：2020-05-13

申请号：EP18828059.8

申请日：2018-07-05

Applicant: Yamada, Ken-Ichi ,  Fuso Pharmaceutical Industries, Ltd.

Inventor： YAMADA, Ken-ichi ,  SHINTO, Saki ,  IDE, Tomomi ,  YAMAMOTO, Keiichi

IPC: G01N33/50 ,  A61K31/198 ,  A61K31/245 ,  A61K31/4045 ,  A61K31/407 ,  A61K31/47 ,  A61K31/473 ,  A61K31/5513 ,  A61P1/16 ,  A61P9/00 ,  A61P9/10 ,  A61P11/06 ,  A61P13/12 ,  A61P25/00 ,  A61P25/16 ,  A61P25/28 ,  A61P27/02 ,  A61P35/00 ,  A61P43/00 ,  G01N33/15

Abstract: The present invention provides: an assay method that uses a compound represented by formula (I) as a fluorescent probe molecule and that is for detecting the lipid peroxidation suppression activity of a test compound; an assay kit that uses the assay method; a screening method that uses the assay method; and a pharmaceutical composition that is for the treatment, etc. of diseases (such as age-related macular degeneration) that are induced by lipid peroxidation reactions.