公开(公告)号：EP2864051A4

公开(公告)日：2016-04-06

申请号：EP13809442

申请日：2013-06-25

申请人： GEN HOSPITAL CORP

发明人： SMITH KYLE C ,  HAGHOOGIE RAMIN ,  BARBER THOMAS ALAN ,  OZKUMUR ISMAIL EMRE ,  KAPUR RAVI ,  TONER MEHMET

IPC分类号： B03C1/28 ,  B03C1/01 ,  B03C1/32 ,  G01N33/487 ,  G01N33/547

CPC分类号： B01L3/502761 ,  B01L2200/0652 ,  B01L2200/0668 ,  B01L2200/12 ,  B01L2300/06 ,  B01L2300/12 ,  B01L2400/043 ,  B03C1/0332 ,  B03C1/288 ,  B03C2201/18 ,  B03C2201/26 ,  G01N1/4077 ,  G01N33/48735 ,  G01N33/54333

摘要： This disclosure describes microfluidic devices that include one or more magnets, each magnet being operable to emit a magnetic field; and a magnetizable layer adjacent to the one or more magnets, in which the magnetizable layer is configured to induce a gradient in the magnetic field of at least one of the magnets. For example, the gradient can be at least 103 T/m at a position that is at least 20 μm away from a surface of the magnetizable layer. The magnetizable layer includes a first high magnetic permeability material and a low magnetic permeability material arranged adjacent to the high magnetic permeability material. The devices also include a microfluidic channel arranged on a surface of the magnetizable layer, wherein a central longitudinal axis of the microfluidic channel is arranged at an angle to or laterally offset from an interface between the high magnetic permeability material and the low magnetic permeability material.

摘要翻译： 本公开描述了包括一个或多个磁体的微流体装置，每个磁体可操作以发射磁场; 以及与所述一个或多个磁体相邻的可磁化层，其中所述可磁化层被配置为在至少一个所述磁体的磁场中引起梯度。 例如，在距可磁化层的表面至少20μm的位置处，梯度可以至少为103T / m。 可磁化层包括第一高磁导率材料和邻近高磁导率材料布置的低磁导率材料。 这些装置还包括布置在可磁化层的表面上的微流体通道，其中微流体通道的中心纵向轴线与高磁导率材料和低磁导率材料之间的界面成角度或横向偏移。