公开(公告)号：EP1576042A4

公开(公告)日：2006-11-08

申请号：EP03796535

申请日：2003-11-26

申请人： GENENCOR INT ,  DOW CORNING

发明人： JENSEN RASMUS B ,  KELEMEN BRADLEY R ,  MCAULIFFE JOSEPH C ,  SMITH WYATT C

IPC分类号： C07H21/04 ,  C07K14/705 ,  C12Q1/68 ,  F21L4/04 ,  G11B7/246 ,  G11B7/24 ,  G11B20/10 ,  G11C13/04

CPC分类号： G11B7/245 ,  B42D25/378 ,  B42D2035/24 ,  C07H21/04 ,  C07K14/195 ,  C07K14/705 ,  C09D11/037 ,  G11B7/246 ,  G11B7/2531 ,  G11B7/2532 ,  G11B7/2533 ,  G11B7/2539 ,  Y10S430/146

摘要： The present invention relates to materials comprising hydrophilic polymersand immobilized proteorhodopsin and the use of such materials as an optical information carrier. The material comprises one or more hydrophilic polymersthat are capable to form a homogeneous phase with proteorhodopsin prior to solidification to a solid form. The hydrophilic polymer, for example, is silica sol-gel,gelatin, polyvinylalcohol, agarose, agar, methyl cellulose, polyvinyl acetate, polyvinyl pyrrolidone, polyethylene glycol, or a mixture thereof. The solid material having immobilized proteorhodopsin is deposited on a substrate selected from the group consisting of glass, paper, metal, fabric material, plastic material, and used as an optical data storage material or a fraud-proof carrier. The present invention further provides a security ink comprising proteorhodopsin and one or more hydrophilicpolymers.

摘要翻译： 本发明涉及包含亲水性聚合物和固定的蛋白质视紫红质的材料以及这种材料作为光学信息载体的用途。 该材料包含一种或多种能够在固化成固体形式之前与蛋白质视紫质形成均相的亲水性聚合物。 亲水性聚合物例如是硅溶胶 - 凝胶，明胶，聚乙烯醇，琼脂糖，琼脂，甲基纤维素，聚乙酸乙烯酯，聚乙烯吡咯烷酮，聚乙二醇或它们的混合物。 具有固定化蛋白质视紫红质的固体材料沉积在选自玻璃，纸，金属，织物材料，塑料材料的基材上，并用作光学数据存储材料或防欺负载体。 本发明还提供了包含蛋白视紫红质和一种或多种亲水性聚合物的安全油墨。

公开(公告)号：EP1576144A4

公开(公告)日：2007-02-14

申请号：EP03811664

申请日：2003-11-26

申请人： GENENCOR INT ,  DOW CORNING

发明人： JENSEN RASMUS B ,  KELEMEN BRADLEY R

IPC分类号： C07H21/04 ,  C07K14/705 ,  C12Q1/68 ,  F21L4/04 ,  G11B7/246 ,  C12N15/31 ,  C07K14/195 ,  G11B7/24 ,  G11B20/10 ,  G11C13/04

CPC分类号： C07H21/04 ,  B42D2035/24 ,  C07K14/195 ,  C07K14/705 ,  G11B7/245 ,  G11B7/246 ,  G11B7/2531 ,  G11B7/2532 ,  G11B7/2533 ,  G11B7/2539

摘要： The present invention is directed to a protoeorhodopsin mutant having improved optical characteristics. One improved optical characteristic is having a lower pH(pKrh) at which equal concentrations of the acidic and basic spectral form of the proteorrhodopsin molecules are present. Another improved optical characteristic is having a smaller difference in maximum absorption wavelength between the basic and the acidic form. The mutant comprises a mutation in a conserved amino acid residue of a proteorhodopdin variant, which auses spectral shifts. A preferred mutation site is a conserved histidine residue at amino acid position 75 of Bac31A8, or position 77 of Hot75m1, or its equivalent position of a proteorhodopsin variant. Another preferred mutation site is a conserved arginine residue at amino acid position 94 of Bac31A8, or position 96 of Hot75m1, or its equivalent position of a proteorhodopsin variant.

公开(公告)号：EP1753448A4

公开(公告)日：2009-09-02

申请号：EP05761082

申请日：2005-06-09

申请人： GENENCOR INT ,  DOW CORNING

发明人： BOTT RICHARD R ,  JENSEN RASMUS B ,  KELEMEN BRADLEY ,  WARD DONALD E II ,  WHITED GREGORY M

IPC分类号： C07K14/00 ,  A61K38/17 ,  C07K14/215 ,  C07K14/705 ,  C09D11/00

CPC分类号： G11C7/00 ,  C07K14/215 ,  C09D11/037 ,  C09D11/50 ,  G11B7/242 ,  Y10S430/146 ,  Y10T428/249921 ,  Y10T428/31623 ,  Y10T428/31685 ,  Y10T428/31725 ,  Y10T428/31783

摘要： The present invention provides a solid material comprising an immobilized mixture of two or more proteorhodopsins, two or more bacteriorhodopsins, or one or more bacteriorhodopsin and one or more proteorhodopsins. The proteorhodopsins are selected from the group consisting of all-trans-retinal-containing proteorhodopsins and retinal analog-containing proteorhodopsins; all of which have absorption spectra that do not overlap. The bacteriorhodopsins are selected from the group consisting of all-trans-retinal- containing bacteriorhodopsins and retinal analog-containing bacteriorhodopsins; all of which have absorption spectra that do not overlap. The present invention also provides an optical information carrier, such as an optical data storage material and a fraud-proof optical data carrier, comprising the above-described solid material and a substrate selected from the group consisting of glass, paper, metal, fabric material, and plastic material, wherein said solid material is deposited on said substrate. The present invention further provides security ink comprising one or more hydrophilic polymers and a mixture of various photochromic materials.

摘要翻译： 本发明提供一种固体材料，其包含两种或更多种proteorhodopsins，两种或更多种细菌视紫红质或一种或更多种细菌视紫红质和一种或更多种proteorhodopsins的固定化混合物。 该proteorhodopsins选自全反式视网膜proteorhodopsins和含视网膜类似物proteorhodopsins; 所有这些都具有不重叠的吸收光谱。 细菌视紫红质选自含全反式视黄醛的细菌视紫红质和含视网膜模拟物的细菌视紫红质; 所有这些都具有不重叠的吸收光谱。 本发明还提供一种光学信息载体，例如光学数据存储材料和防欺诈光学数据载体，其包括上述固体材料和选自玻璃，纸，金属，织物材料 和塑料材料，其中所述固体材料沉积在所述基材上。 本发明进一步提供包含一种或多种亲水性聚合物和各种光致变色材料的混合物的安全油墨。

公开(公告)号：EP1753997A4

公开(公告)日：2008-06-18

申请号：EP05771676

申请日：2005-06-09

申请人： GENENCOR INT ,  DOW CORNING

发明人： JENSEN RASMUS B ,  KELEMEN BRADLEY ,  WARD DONALD E II ,  ASATO ALFRED E

IPC分类号： A61K31/07 ,  A61K31/19 ,  A61K31/20 ,  A61K31/215 ,  A61K31/275 ,  A61K38/17 ,  C07C47/225 ,  C07C47/24 ,  C07C47/548 ,  F21V9/00 ,  G02B5/23

CPC分类号： C07C403/14 ,  A61K31/07 ,  A61K31/19 ,  A61K31/20 ,  A61K31/215 ,  A61K31/275 ,  A61K38/1709 ,  C07C47/225 ,  C07C47/24 ,  C07C47/548 ,  C07C2601/16 ,  C07C2602/30 ,  G02B5/23 ,  A61K2300/00

摘要： The present invention relates to a photochromic material comprising a proteorhodopsin apoprotein and a retinal analog. In one embodiment, the retinal analog is an azulenic retinoid compound. In another embodiment, the retinal analog is other compound that is structurally similarly to all-trans-retinal. The proteorhodopsin apoprotein and the retinal analog form a photochromic material having different spectral properties from those of a corresponding photochromic material formed by the same proteorhodopsin apoprotein and all-trans-retinal. In one embodiment of the application, the retinal analog-containing proteorhodopsin has an absorbance spectrum that does not overlap significantly with that of all-trans-retinal-containing proteorhodopsin. In another embodiment of the application, the retinal analog-containing proteorhodopsin yields a red-shifted visual chromophore compared with the all-trans-retinal-containing proteorhodopsin chromophore. The photochromic material of the present invention is useful as an optical data storage carrier, a fraud-proof optical data carrier, security ink, and in other optical applications.