摘要:
he present invention provides plasmids suitable as vector systems for filamentous fungi, especially antibiotic-producing filamentous fungi such as antibiotic-producing strains of Acremonium chrysogenum or Penicillium chrysogenum, comprising an autonomous replication sequence which is effective in the intended host, an activator sequence derived from, or copied from, DNA of the intended host and/or one or more other fungi of the same species, and a fungal selectable protein-coding element, transcription of which is directed by the activator sequence.
摘要:
he present invention provides plasmids suitable as vector systems for filamentous fungi, especially antibiotic-producing filamentous fungi such as antibiotic-producing strains of Acremonium chrysogenum or Penicillium chrysogenum, comprising an autonomous replication sequence which is effective in the intended host, an activator sequence derived from, or copied from, DNA of the intended host and/or one or more other fungi of the same species, and a fungal selectable protein-coding element, transcription of which is directed by the activator sequence.