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公开(公告)号:EP2970315A4
公开(公告)日:2016-08-17
申请号:EP14768414
申请日:2014-03-10
发明人: LI ZHE , XU QING , METCALF BRIAN W , GWALTNEY II STEPHEN L , HARRIS JASON R , YEE CALVIN W
IPC分类号: A61K31/437 , A61P7/00 , C07D231/12 , C07D401/04 , C07D403/04 , C07D405/04 , C07D413/04
CPC分类号: C07D413/04 , C07D231/12 , C07D401/04 , C07D403/04 , C07D405/04
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公开(公告)号:EP2968299A4
公开(公告)日:2016-08-24
申请号:EP14769616
申请日:2014-03-10
发明人: LI ZHE , XU QING , METCALF BRIAN W , GWALTNEY II STEPHEN L , HARRIS JASON R , YEE CALVIN W
IPC分类号: A61K31/437 , A61P7/00 , C07D213/74 , C07D401/04 , C07D405/04 , C07D413/04 , C07D498/08
CPC分类号: C07D498/08 , C07D213/74 , C07D401/04 , C07D405/04 , C07D491/107
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公开(公告)号:EP2970196A4
公开(公告)日:2016-08-17
申请号:EP14770695
申请日:2014-03-10
发明人: XU QING , LI ZHE , GWALTNEY II STEPHEN L
IPC分类号: C07D487/04 , A61K31/437 , A61P7/00 , C07C65/30 , C07D207/08 , C07D211/30 , C07D211/62 , C07D213/30 , C07D213/64 , C07D231/56 , C07D257/04 , C07D265/30 , C07D401/04 , C07D401/12 , C07D401/14 , C07D403/12 , C07D471/04
CPC分类号: C07D403/12 , C07D207/08 , C07D211/30 , C07D265/30 , C07D401/12
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公开(公告)号:EP2970184A4
公开(公告)日:2016-10-26
申请号:EP14768759
申请日:2014-03-10
发明人: HARRIS JASON R , METCALF BRIAN W , LI ZHE , GWALTNEY II STEPHEN L
IPC分类号: C07D401/04 , A61K31/4155 , A61K31/4439 , C07D403/04
CPC分类号: C07D401/04
摘要: Provide herein are compounds and pharmaceutical compositions suitable as modulators of hemoglobin, methods and intermediates for their preparation, and methods for their use in treating disorders mediated by hemoglobin and disorders that would benefit from tissue and/or cellular oxygenation.
摘要翻译: 本文提供适合作为血红蛋白调节剂,其制备方法和中间体的化合物和药物组合物,及其用于治疗由血红蛋白介导的病症和可受益于组织和/或细胞氧合的病症的方法。
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