-
公开(公告)号：EP1315511A4
公开(公告)日：2005-10-19
申请号：EP01957133
申请日：2001-07-12
发明人： KOCHENDOERFER GERD , BOTTI PAOLO , BRADBURNE JAMES A , CHEN SHIAH-YUN , CRESSMAN SONYA , HUNTER CHRISTIE L , KENT STEPHEN B H , LOW DONALD W
IPC分类号： A61K38/00 , A61K38/02 , A61K38/22 , A61K47/34 , A61K47/42 , A61K47/48 , A61P7/00 , A61P7/06 , A61P9/10 , A61P11/02 , A61P11/06 , A61P17/00 , A61P19/02 , A61P29/00 , A61P31/12 , A61P37/06 , A61P37/08 , A61P43/00 , C07K1/00 , C07K1/06 , C07K14/47 , C07K14/505 , C07K14/52 , C07K17/08 , C07K19/00
CPC分类号： C07K14/505 , A61K38/00
-
">
公开(公告)号：EP1315513A4
公开(公告)日：2005-09-21
申请号：EP01952657
申请日：2001-07-12
发明人： KENT STEPHEN B H , BOTTI PAOLO , LOW DONALD W , BRADBURNE JAMES A , HUNTER CHRISTIE L , CHEN SHIAH-YUN , CRESSMAN SONYA , KOCHENDOERFER GERD
IPC分类号： A61K38/00 , A61K38/02 , A61K38/22 , A61K47/34 , A61K47/42 , A61K47/48 , A61P7/00 , A61P7/06 , A61P9/10 , A61P11/02 , A61P11/06 , A61P17/00 , A61P19/02 , A61P29/00 , A61P31/12 , A61P37/06 , A61P37/08 , A61P43/00 , C07K1/00 , C07K1/06 , C07K14/47 , C07K14/505 , C07K14/52 , C07K17/08 , C07K19/00 , A61K38/18 , A61K38/19 , A61K38/20 , A61K38/21 , A61K38/27 , C07K1/02 , C07K2/00 , C07K14/475 , C07K14/525 , C07K14/535 , C07K14/54 , C07K14/555 , C07K14/575
CPC分类号： C07K14/505 , A61K38/00
摘要： The present invention concerns methods and compositions for extending the technique of native chemical ligation of a wider range of peptides, polypeptides, other polymers and other molecules via an amide bond (see FIG. 1 ). The invention further provides methods and uses for such proteins and derivatized proteins. The invention is particularly suitable for use in the synthesis of optionally polymer-modified, synthetic bioactive proteins, and of pharmaceutical compositions that contain such proteins.
-
3.发明公开POLYMER-MODIFIED BIOACTIVE SYNTHETIC CHEMOKINES, AND METHODS FOR THEIR MANUFACTURE AND USE 审中-公开聚合物改性的生物活性合成趋化因子和制备方法和用途FOR THEIR
公开(公告)号：EP1307216A4
公开(公告)日：2005-01-12
申请号：EP01952656
申请日：2001-07-12
IPC分类号： A61K47/30 , A61K38/00 , A61K38/19 , A61K45/00 , A61K47/34 , A61K47/48 , A61P9/10 , A61P11/06 , A61P17/00 , A61P27/16 , A61P29/00 , A61P35/00 , A61P37/00 , A61P37/08 , C07H21/04 , C07K14/47 , C07K14/52 , C07K14/715 , C07K19/00 , C12P21/02
CPC分类号： C07K14/7158 , A61K38/00 , A61K47/60 , A61K47/62
摘要： The invention relates to polymer-modified bioactive synthetic chemokines and to methods for their production and use. The bioactive synthetic chemokines of the invention comprises a polymer modified polypeptide chemokine backbone. The compounds and methods or the invention are useful for the treatment of disorders involving naturally occurring chemokines, such as for the treatment of HIV and AIDS related disorders and for the treatment of asthma, allergic rhinitis, atopic dermatitis, atheroma/atherosclerosis, organ transplant rejection, and rheumatoid arthritis.
-
-
搜索结果
3 条记录 (耗时 0.011 秒)
