AUS GELEE ROYALE ISOLIERTES ANTIVIRAL WIRKSAMES OLIGOPEPTID
    2.
    发明公开
    AUS GELEE ROYALE ISOLIERTES ANTIVIRAL WIRKSAMES OLIGOPEPTID 审中-公开
    蜂王浆隔离抗病毒有效寡肽

    公开(公告)号:EP1042364A2

    公开(公告)日:2000-10-11

    申请号:EP98965731.7

    申请日:1998-12-02

    IPC分类号: C07K14/435 A61K38/17

    摘要: The invention relates to a family of oligopeptides with a completely new structure which occurs in selectively obtained royal jellies of certain vegetable origin and has been correlated with marked antiviral properties. The pilot structure is a molecule with 52 amino acids. Numerous analogous, nearly identical molecules are present in a satellite-like manner. The substances have a broad spectrum of antiviral activity, including against retroviruses, and have no toxic effect on humans even at high doses. A further surprising characteristic is their extreme resistance to all controlled proteases and other enzymes. The molecules are highly convoluted and resistant to attack. Despite their convolution they are geometrically very flexible and can form several conformers. The native state is easily soluble in water. Chemical synthesis results in a water insoluble form which can, however, be easily transformed into a soluble bioactive conformer which is similar to the native form. These new oligopeptides are therefore the first to combine in an optimal manner all the properties required of a potentially antiviral substance category.

    GELEE-ROYALE
    4.
    发明授权

    公开(公告)号:EP0663833B1

    公开(公告)日:1996-10-16

    申请号:EP93920795.7

    申请日:1993-09-22

    发明人: BENGSCH, Eberhard

    IPC分类号: A61K35/64 A23L1/076

    CPC分类号: A61K35/644 A23L21/20

    摘要: The invention pertains to royal jelly, a method of extracting it and its use. The aim of the invention is to make a standarized product. This is achieved by means of suction with an inert gas.

    摘要翻译: 本发明涉及蜂王浆,其提取方法及其用途。 本发明的目的是制造标准化产品。 这是通过用惰性气体抽吸来实现的。

    VERFAHREN ZUR BESTIMMUNG DER ANZAHL VON KOMPONENTEN IN PEAKS, BANDEN UND SIGNALEN VON CHROMATOGRAMMEN, ELEKTROGRAMMEN UND SPEKTROGRAMMEN ALLER ART
    6.
    发明公开
    VERFAHREN ZUR BESTIMMUNG DER ANZAHL VON KOMPONENTEN IN PEAKS, BANDEN UND SIGNALEN VON CHROMATOGRAMMEN, ELEKTROGRAMMEN UND SPEKTROGRAMMEN ALLER ART 失效
    用于确定组件技术在PEAKS,帮派和信号的色谱,电描记数法和频谱图任何形式

    公开(公告)号:EP0993609A1

    公开(公告)日:2000-04-19

    申请号:EP98929409.5

    申请日:1998-06-02

    IPC分类号: G01N30/86 G01N30/82

    摘要: A process is disclosed for determining the number of components in peaks, bands and signals of chromatograms, electrograms and spectrograms of all types obtained for purposes of analysis and substance separation in spectrograms of all types wherever energy-correlated measurement values as a function of an evolving parameter are formed and decomposed again. The problem addressed by the invention is that of designing a simple process. This problem is solved in that the different energy-correlated measurement values of a family of such measurement values produced from such a parameter are mutually related, so that characteristic geometric figures are obtained in which the originating evolving parameters are no longer contained. The thus obtained figures are gradually reduced, depending on their complexity, into straight lines, then into points. The number of components which contribute to the peaks and thus the composition of the total spectrogram in terms of the elements that make it up are obtained by the most simple manner, as well as the composition of the mixture of substances to be analysed and/or separated,.