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公开(公告)号：EP1234036A2
公开(公告)日：2002-08-28
申请号：EP00991686.7
申请日：2000-11-10
申请人： Genentech, Inc.
发明人： FONG, Sherman , GODDARD, Audrey , GODOWSKI, Paul, J. , GRIMALDI, Christopher, J. , GURNEY, Austin, L. , HILLAN, Kenneth, J. , TUMAS, Daniel , WATANABE, Colin, K. , WOOD, William, I. , ZHANG, Zemin
IPC分类号： C12N15/12 , C07K14/47 , C12N15/62 , C07K16/18 , A61K38/17 , A61K39/395 , G01N33/53 , C12Q1/68
CPC分类号： A61K38/17 , A61K39/395 , C07K14/47 , C07K16/18 , C12N15/62 , C12Q1/68 , G01N33/53 , Y02A50/464
摘要： The present invention relates to compositions containing novel proteins and methods of using those compositions for the diagnosis and treatment of immune related diseases.
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2.发明授权
公开(公告)号：EP1240325B1
公开(公告)日：2009-09-30
申请号：EP00989401.5
申请日：2000-12-20
申请人： Genentech, Inc.
发明人： CHEN, Jian , FILVAROFF, Ellen , FONG, Sherman , GODDARD, Audrey , GODOWSKI, Paul, J. , GRIMALDI, Christopher, J. , GURNEY, Austin, L. , LI, Hanzhong , HILLAN, Kenneth, J. , TUMAS, Daniel , VAN LOOKEREN, Menno , VANDLEN, Richard, L. , WATANABE, Colin, K. , WILLIAMS, P., Mickey , WOOD, William, I. , YANSURA, Daniel, G.
IPC分类号： C12N15/12 , C07K14/715 , C07K14/54 , C12N15/62 , C07K16/24 , C07K16/28 , A61K31/70 , A61K38/17 , A61K38/20 , A61K39/395 , G01N33/566 , G01N33/53
CPC分类号： C07K14/54 , C07K14/7155
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3.发明公开SECRETED AMD TRANSMEMBRANE POLYPEPTIDES AND NUCLEIC ACIDS ENCODING THE SAME 审中-公开分泌的AMD跨膜多肽和编码相同的核酸
公开(公告)号：EP1135495A2
公开(公告)日：2001-09-26
申请号：EP99968054.9
申请日：1999-12-01
申请人： Genentech, Inc.
发明人： BAKER, Kevin, P. , BOTSTEIN, David , EATON, Dan, L. , FERRARA, Napoleone , FILVAROFF, Ellen , GERRITSEN, Mary, E. , GODDARD, Audrey , GODOWSKI, Paul, J. , GRIMALDI, Christopher, J. , GURNEY, Austin, L. , HILLAN, Kenneth, J. , KLJAVIN, Ivar, J. , NAPIER, Mary, a. , ROY, Margaret, Ann , TUMAS, Daniel , WOOD, William, I.
CPC分类号： C07K14/4748 , A61K38/00 , C07K14/47 , C07K14/4703 , C07K16/18 , C07K2317/24 , C07K2319/00 , C07K2319/02
摘要： The present invention is directed to secreted and transmembrane polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
摘要翻译： 本发明涉及分泌和跨膜多肽和编码那些多肽的核酸分子。 本文还提供了包含那些核酸序列的载体和宿主细胞，包含与异源多肽序列融合的本发明多肽的嵌合多肽分子，结合本发明多肽的抗体以及产生本发明多肽的方法 发明。
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4.发明公开
公开(公告)号：EP1240325A2
公开(公告)日：2002-09-18
申请号：EP00989401.5
申请日：2000-12-20
申请人： Genentech, Inc.
发明人： CHEN, Jian , FILVAROFF, Ellen , FONG, Sherman , GODDARD, Audrey , GODOWSKI, Paul, J. , GRIMALDI, Christopher, J. , GURNEY, Austin, L. , LI, Hanzhong , HILLAN, Kenneth, J. , TUMAS, Daniel , VAN LOOKEREN, Menno , VANDLEN, Richard, L. , WATANABE, Colin, K. , WILLIAMS, P., Mickey , WOOD, William, I. , YANSURA, Daniel, G.
IPC分类号： C12N15/12 , C07K14/715 , C07K14/54 , C12N15/62 , C07K16/24 , C07K16/28 , A61K31/70 , A61K38/17 , A61K38/20 , A61K39/395 , G01N33/566 , G01N33/53
CPC分类号： C07K14/54 , C07K14/7155
摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号：EP1208202A2
公开(公告)日：2002-05-29
申请号：EP00964919.5
申请日：2000-08-24
申请人： Genentech, Inc.
发明人： EATON, Dan, L. , FILVAROFF, Ellen , GERRITSEN, Mary, E. , GODDARD, Audrey , GODOWSKI, Paul, J. , GRIMALDI, Christopher, J. , GURNEY, Austin, L. , WATANABE, Colin, K. , WOOD, William, I.
CPC分类号： C07K14/47 , C07K14/705
摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号：EP1485477B1
公开(公告)日：2009-05-13
申请号：EP03709321.8
申请日：2003-02-24
申请人： Genentech, Inc.
发明人： DE SAUVAGE, Frederic, J. , GHILARDI, Nico, P. , GODDARD, Audrey , GODOWSKI, Paul, J. , GRIMALDI, Christopher, J. , GURNEY, Austin, L. , WOOD, William, I.
CPC分类号： C07K14/7158
摘要： The present invention is directed to novel polypeptides and variants thereof of GLM-R polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Also provided are methods for detecting agents that modulate the activity of GLM-R. Also provided are methods for diagnosing and for treating disorders characterized by the over or under abundance of monocytes or macrophages.
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公开(公告)号：EP1485477A2
公开(公告)日：2004-12-15
申请号：EP03709321.8
申请日：2003-02-24
申请人： Genentech, Inc.
发明人： DE SAUVAGE, Frederic, J. , GHILARDI, Nico, P. , GODDARD, Audrey , GODOWSKI, Paul, J. , GRIMALDI, Christopher, J. , GURNEY, Austin, L. , WOOD, William, I.
CPC分类号： C07K14/7158
摘要： The present invention is directed to novel polypeptides and variants thereof of GLM-R polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Also provided are methods for detecting agents that modulate the activity of GLM-R. Also provided are methods for diagnosing and for treating disorders characterized by the over or under abundance of monocytes or macrophages.
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