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公开(公告)号：EP1029046A2
公开(公告)日：2000-08-23
申请号：EP98954038.0
申请日：1998-10-29
申请人： Genentech, Inc.
发明人： LEVINE, Arnold, J. , PENNICA, Diane
CPC分类号： G01N33/57484 , C07K14/47 , C07K2317/24 , C07K2319/02 , G01N33/68
摘要： DNAs are provided, whose genes are induced at least by Wnt-1. Also provided are nucleic acid molecules encoding those polypeptides, as well as vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides, and methods for producing the polypeptides.
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公开(公告)号：EP1027437B8
公开(公告)日：2008-10-29
申请号：EP98956340.8
申请日：1998-10-29
申请人： Genentech, Inc.
发明人： BOTSTEIN, David, A. , COHEN, Robert, L. , GURNEY, Austin, L. , HILLAN, Kenneth , LAWRENCE, David, A. , LEVINE, Arnold, J. , PENNICA, Diane , ROY, Margaret, Ann , GODDARD, Audrey , WOOD, William, I.
CPC分类号： C07K14/47 , C07K14/475 , C07K16/18 , C07K16/22 , C07K16/30 , C07K16/32 , C07K2317/73 , C07K2317/74 , C12Q1/6886 , C12Q2600/136
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公开(公告)号：EP1029046B1
公开(公告)日：2008-09-24
申请号：EP98954038.0
申请日：1998-10-29
申请人： Genentech, Inc.
发明人： LEVINE, Arnold, J. , PENNICA, Diane
CPC分类号： G01N33/57484 , C07K14/47 , C07K2317/24 , C07K2319/02 , G01N33/68
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公开(公告)号：EP1027437B1
公开(公告)日：2008-08-27
申请号：EP98956340.8
申请日：1998-10-29
申请人： GENENTECH, INC.
发明人： BOTSTEIN, David, A. , COHEN, Robert, L. , GURNEY, Austin, L. , HILLAN, Kenneth , LAWRENCE, David, A. , LEVINE, Arnold, J. , PENNICA, Diane , ROY, Margaret, Ann , GODDARD, Audrey , WOOD, William, I.
CPC分类号： C07K14/47 , C07K14/475 , C07K16/18 , C07K16/22 , C07K16/30 , C07K16/32 , C07K2317/73 , C07K2317/74 , C12Q1/6886 , C12Q2600/136
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公开(公告)号：EP1027437A1
公开(公告)日：2000-08-16
申请号：EP98956340.8
申请日：1998-10-29
申请人： Genentech, Inc.
发明人： BOTSTEIN, David, A. , COHEN, Robert, L. , GURNEY, Austin, L. , HILLAN, Kenneth , LAWRENCE, David, A. , LEVINE, Arnold, J. , PENNICA, Diane , ROY, Margaret, Ann , GODDARD, Audrey , WOOD, William, I.
CPC分类号： C07K14/47 , C07K14/475 , C07K16/18 , C07K16/22 , C07K16/30 , C07K16/32 , C07K2317/73 , C07K2317/74 , C12Q1/6886 , C12Q2600/136
摘要： Wnt-1-Induced Secreted Proteins (WISPs) are provided, whose genes are induced at least by Wnt-1. Also provided are nucleic acid molecules encoding those polypeptides, as well as vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides, and methods for producing the polypeptides.
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