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公开(公告)号：EP2014770A3
公开(公告)日：2009-02-18
申请号：EP08012474.6
申请日：1998-10-29
申请人： Genentech, Inc.
发明人： Botstein, David, A. , Cohen, Robert, L. , Gurney, Austin, L. , Hillan, Kenneth , Lawrence, David, A. , Levine, Arnold, J. , Pennica, Diane , Roy, Margaret, Ann , Goddard, Audrey , Wood, William, I.
CPC分类号： C07K14/47 , C07K14/475 , C07K16/18 , C07K16/22 , C07K16/30 , C07K16/32 , C07K2317/73 , C07K2317/74 , C12Q1/6886 , C12Q2600/136
摘要： Wnt-l-Induced Secreted Proteins (WISPs) are provided, whose genes are induced at least by Wnt-1. Also provided are nucleic acid molecules encoding those polypeptides, as well as vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides, and methods for producing the polypeptides.
摘要翻译： 提供了Wnt-1诱导的分泌蛋白（WISPs），其基因至少由Wnt-1诱导。 还提供了编码那些多肽的核酸分子，以及包含那些核酸序列的载体和宿主细胞，包含与异源多肽序列融合的多肽的嵌合多肽分子，与多肽结合的抗体以及用于产生多肽的方法。
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公开(公告)号：EP2014770A2
公开(公告)日：2009-01-14
申请号：EP08012474.6
申请日：1998-10-29
申请人： Genentech, Inc.
发明人： Botstein, David, A. , Cohen, Robert, L. , Gurney, Austin, L. , Hillan, Kenneth , Lawrence, David, A. , Levine, Arnold, J. , Pennica, Diane , Roy, Margaret, Ann , Goddard, Audrey , Wood, William, I.
CPC分类号： C07K14/47 , C07K14/475 , C07K16/18 , C07K16/22 , C07K16/30 , C07K16/32 , C07K2317/73 , C07K2317/74 , C12Q1/6886 , C12Q2600/136
摘要： Wnt-l-Induced Secreted Proteins (WISPs) are provided, whose genes are induced at least by Wnt-1. Also provided are nucleic acid molecules encoding those polypeptides, as well as vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides, and methods for producing the polypeptides.
摘要翻译： 提供了Wnt-1诱导的分泌蛋白（WISP），其基因至少被Wnt-1诱导。 还提供了编码那些多肽的核酸分子，以及包含那些核酸序列的载体和宿主细胞，包含与异源多肽序列融合的多肽的嵌合多肽分子，与多肽结合的抗体，以及用于产生多肽的方法。
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