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公开(公告)号：EP2091565A2
公开(公告)日：2009-08-26
申请号：EP07868886.8
申请日：2007-11-28
申请人： Genentech, Inc.
IPC分类号： A61K45/00 , A61K45/06 , A61P35/00 , G01N33/574
CPC分类号： A61K31/00 , A61K45/06 , G01N33/57407
摘要： The present invention is directed to methods and compositions for the diagnosis, prognosis and treatment of glioma in mammals.
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公开(公告)号：EP1613660B1
公开(公告)日：2012-12-19
申请号：EP04759921.2
申请日：2004-04-16
申请人： Genentech, Inc.
发明人： ACKERLY, Heidi , ASHKENAZI, Avi , EBERHARD, David , FRANTZ, Gretchen , FRENCH, Dorothy , FUH, Germaine , HONGO, Jo-Anne , LEE, Chingwei , MARSTERS, Scot , PITTI, Robert , RAAB, Helga , SOROCEANU, Liliana , VARFOLOMEEV, Evgeny , WOLF, Beni
IPC分类号： C07K16/44 , C07K14/47 , G01N33/53 , A61P35/00 , C12N15/12 , C12N15/63 , C12N15/09 , A61K31/7088 , C07K19/00
CPC分类号： C07K16/32 , C07K16/22 , C07K16/4283 , C07K2317/24 , C07K2317/54 , C07K2317/55 , C07K2317/565 , C07K2317/622
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公开(公告)号：EP1613660A2
公开(公告)日：2006-01-11
申请号：EP04759921.2
申请日：2004-04-16
申请人： GENENTECH, INC.
发明人： ACKERLY, Heidi , ASHKENAZI, Avi , EBERHARD, David , FRANTZ, Gretchen , FRENCH, Dorothy , FUH, Germaine , HONGO, Jo-Anne , LEE, Chingwei , MARSTERS, Scot , PITTI, Robert , RAAB, Helga , SOROCEANU, Liliana , VARFOLOMEEV, Evgeny , WOLF, Beni
IPC分类号： C07K16/44 , C07K14/47 , G01N33/53 , A61P35/00 , C12N15/12 , C12N15/63 , C12N15/09 , A61K31/7088 , C07K19/00
CPC分类号： C07K16/32 , C07K16/22 , C07K16/4283 , C07K2317/24 , C07K2317/54 , C07K2317/55 , C07K2317/565 , C07K2317/622
摘要： The present invention provides novel polypeptides, antibodies, antagonists, agonists, potentiators, nucleic acid molecules, compositions and methods relating to the STOP-1 polypeptide that are useful for treating and preventing diseases and for medical diagnosis and research. The present invention also provides consensus sequences and specific sequences for antibodies that specifically bind to STOP-1 that are useful in the methods described herein.
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