公开(公告)号：EP2083018A2

公开(公告)日：2009-07-29

申请号：EP09004416.5

申请日：2004-04-16

申请人： Genentech, Inc.

发明人： Ackerly, Heidi ,  Ashkenazi, Avi ,  Eberhard, David ,  Frantz, Gretchen ,  French, Dorothy ,  Fuh, Germaine ,  Hongo, Jo-Anne ,  Lee, Chingwei ,  Marsters, Scot ,  Pitti, Robert ,  Raab, Helga ,  Soroceanu, Liliana ,  Varfolomeev, Evgeny ,  Wolf, Beni

IPC分类号： C07K16/44 ,  C07K14/47 ,  G01N33/53 ,  A61P35/00 ,  C12N15/12 ,  C12N15/63 ,  C12N15/09 ,  A61K31/7088 ,  C07K19/00

CPC分类号： C07K16/32 ,  C07K16/22 ,  C07K16/4283 ,  C07K2317/24 ,  C07K2317/54 ,  C07K2317/55 ,  C07K2317/565 ,  C07K2317/622

摘要： The present invention provides novel polypeptides, antibodies, antagonists, agonists, potentiators, nucleic acid molecules, compositions and methods relating to the STOP-1 polypeptide that are useful for treating and preventing diseases and for medical diagnosis and research. The present invention also provides consensus sequences and specific sequences for antibodies that specifically bind to STOP-1 that are useful in the methods described herein.

摘要翻译： 本发明提供可用于治疗和预防疾病和用于医学诊断和研究的新型多肽，抗体，拮抗剂，激动剂，增效剂，核酸分子，与STOP-1多肽相关的组合物和方法。 本发明还提供了与本文所述方法有用的特异性结合STOP-1的抗体的共有序列和特异性序列。

公开(公告)号：EP2083018A3

公开(公告)日：2010-05-05

申请号：EP09004416.5

申请日：2004-04-16

申请人： Genentech, Inc.

发明人： Ackerly, Heidi ,  Ashkenazi, Avi ,  Eberhard, David ,  Frantz, Gretchen ,  French, Dorothy ,  Fuh, Germaine ,  Hongo, Jo-Anne ,  Lee, Chingwei ,  Marsters, Scot ,  Pitti, Robert ,  Raab, Helga ,  Soroceanu, Liliana ,  Varfolomeev, Evgeny ,  Wolf, Beni

IPC分类号： C07K16/44 ,  C07K14/47 ,  G01N33/53 ,  A61P35/00 ,  C12N15/12 ,  C12N15/63 ,  C12N15/09 ,  A61K31/7088 ,  C07K19/00 ,  C07K16/46 ,  A61K39/395 ,  G01N33/574

CPC分类号： C07K16/32 ,  C07K16/22 ,  C07K16/4283 ,  C07K2317/24 ,  C07K2317/54 ,  C07K2317/55 ,  C07K2317/565 ,  C07K2317/622

摘要： The present invention provides novel polypeptides, antibodies, antagonists, agonists, potentiators, nucleic acid molecules, compositions and methods relating to the STOP-1 polypeptide that are useful for treating and preventing diseases and for medical diagnosis and research. The present invention also provides consensus sequences and specific sequences for antibodies that specifically bind to STOP-1 that are useful in the methods described herein.