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公开(公告)号：EP3309174A1
公开(公告)日：2018-04-18
申请号：EP17188907.4
申请日：2015-05-29
发明人： BOYD, Zachary , KOWANETZ, Marcin , ROCHE, Patrick C. , VENNAPUSA, Bharathi , ZHU, Yifei , LIAO, Zhiming , KOEPPEN, Hartmut
CPC分类号： C07K16/2827 , A61K39/3955 , A61K45/06 , A61N2005/1021 , C07K14/70532 , C07K2317/34 , C07K2317/54 , C07K2317/55 , C07K2317/622 , C07K2317/76 , C07K2319/30 , G01N33/53 , G01N33/57484 , G01N2500/10 , G01N2800/52
摘要： The invention provides programmed death-ligand 1 (PD-L1) antibodies and methods of using the same
摘要翻译： 本发明提供了程序性死亡配体1（PD-L1）抗体及其使用方法
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公开(公告)号：EP3166974A1
公开(公告)日：2017-05-17
申请号：EP15728355.7
申请日：2015-05-29
发明人： VENNAPUSA, Bharathi , LIAO, Zhiming , KOWANETZ, Marcin , BOYD, Zachary , KOEPPEN, Hartmut , ROCHE, Patrick C. , ZHU, Yifei
CPC分类号： C07K16/2827 , A61K39/3955 , A61K45/06 , A61N2005/1021 , C07K14/70532 , C07K2317/34 , C07K2317/54 , C07K2317/55 , C07K2317/622 , C07K2317/76 , C07K2319/30 , G01N33/53 , G01N33/57484 , G01N2500/10 , G01N2800/52
摘要： The invention provides programmed death-ligand 1 (PD-L1) antibodies and methods of using the same.
摘要翻译： 本发明提供了程序性死亡配体1（PD-L1）抗体及其使用方法。
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公开(公告)号：EP3036259A1
公开(公告)日：2016-06-29
申请号：EP14777674.4
申请日：2014-10-02
发明人： SOUKUPOVA, Monika , SCHRAEML, Michael , BOSSENMAIER, Birgit , ROCHE, Patrick C. , GERG, Michael , DZIADEK, Sebastian
IPC分类号： C07K16/32
CPC分类号： C07K16/2863 , C07K16/3023 , C07K16/3046 , C07K16/32 , C07K2317/33 , C07K2317/56 , C07K2317/565 , C07K2317/92 , C07K2317/94 , G01N1/30 , G01N33/57492 , G01N33/74 , G01N2001/302 , G01N2333/71
摘要： The present invention relates to isolated antibodies, or an antigen portions thereof, which bind to human HER3. The novel antibodies are of great utility since they allow for the sensitive and specific detection of human HER3. Detection of human HER3 is, e.g., possible in a tissue sample, even when such tissue sample is a formalin-fixed paraffin embedded tissue (FFPET) sample.
摘要翻译： 本发明涉及与人HER3结合的分离的抗体或其抗原部分。 新型抗体具有很好的实用性，因为它们允许对人HER3的敏感和特异性检测。 即使这样的组织样品是福尔马林固定的石蜡包埋组织（FFPET）样品，人类HER3的检测也可能在组织样品中。
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公开(公告)号：EP2904374A1
公开(公告)日：2015-08-12
申请号：EP13773733.4
申请日：2013-10-07
IPC分类号： G01N1/30
CPC分类号： G01N1/30 , G01N1/312 , G01N2001/302
摘要： Methods, kits, and systems for clarifying obfuscating pigments in histology samples such as an automated method of treating a histology sample with a clarifying reagent so that the clarifying reagent, contacts the sample and the pigments within the sample are decolorized , thus alleviating staining obfuscations associated with pigments. Decolorizing the pigments within the sample enables the histology sample to be interpretable by a qualified reader. An antigen retrieval step is performed after the clarification step.
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公开(公告)号：EP3036259B1
公开(公告)日：2018-02-21
申请号：EP14777674.4
申请日：2014-10-02
发明人： SOUKUPOVA, Monika , SCHRAEML, Michael , BOSSENMAIER, Birgit , ROCHE, Patrick C. , GERG, Michael , DZIADEK, Sebastian
IPC分类号： C07K16/32
CPC分类号： C07K16/2863 , C07K16/3023 , C07K16/3046 , C07K16/32 , C07K2317/33 , C07K2317/56 , C07K2317/565 , C07K2317/92 , C07K2317/94 , G01N1/30 , G01N33/57492 , G01N33/74 , G01N2001/302 , G01N2333/71
摘要： The present invention relates to isolated antibodies, or an antigen portions thereof, which bind to human HER3. The novel antibodies are of great utility since they allow for the sensitive and specific detection of human HER3. Detection of human HER3 is, e.g., possible in a tissue sample, even when such tissue sample is a formalin-fixed paraffin embedded tissue (FFPET) sample.
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