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公开(公告)号:EP4041303A1
公开(公告)日:2022-08-17
申请号:EP20811130.2
申请日:2020-10-09
申请人: Genentech, Inc. , Xencor, Inc.
发明人: DESJARLAIS, John , BERNETT, Matthew , HEDVAT, Michael , VARMA, Rajat , SCHUBBERT, Suzanne , BONZON, Christine , RASHID, Rumana , DIAZ, Juan , HOLDER, Patrick , HUANG, Christine
IPC分类号: A61K39/395 , A61P35/00 , C07K14/54 , C07K14/715 , C07K16/08 , C07K16/28 , A61K39/00
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公开(公告)号:EP3223907A2
公开(公告)日:2017-10-04
申请号:EP15816291.7
申请日:2015-11-25
申请人: Xencor, Inc.
发明人: MOORE, Gregory , DESJARLAIS, John , BERNETT, Matthew , CHU, Seung , RASHID, Rumana , MUCHHAL, Umesh
CPC分类号: C07K16/40 , A61K2039/505 , C07K16/18 , C07K16/2809 , C07K16/2896 , C07K16/3061 , C07K2317/24 , C07K2317/31 , C07K2317/33 , C07K2317/522 , C07K2317/524 , C07K2317/526 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/622 , C07K2317/64 , C07K2317/73 , C07K2317/92
摘要: The present invention is directed to heterodimeric antibodies that bind CD3 and CD38.
摘要翻译: 本发明涉及结合CD3和CD38的异二聚体抗体。
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公开(公告)号:EP4257613A2
公开(公告)日:2023-10-11
申请号:EP23172675.3
申请日:2017-06-14
申请人: Xencor, Inc.
发明人: BERNETT, Matthew , MOORE, Gregory , DESJARLAIS, John , HEDVAT, Michael , BONZON, Christine , NISTHAL, Alex , MUCHHAL, Umesh, S.
IPC分类号: C07K16/46
摘要: The present invention is directed to bispecific, heterodimeric checkpoint antibodies.
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公开(公告)号:EP3928788A1
公开(公告)日:2021-12-29
申请号:EP21173790.3
申请日:2015-11-25
申请人: Xencor, Inc.
发明人: MOORE, Gregory , DESJARLAIS, John , BERNETT, Matthew , CHU, Seung , RASHID, Rumana , MUCHHAL, Umesh , LEE, Sung-Hyung
摘要: The present invention is directed to novel heterodimeric antibodies.
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公开(公告)号:EP3927728A2
公开(公告)日:2021-12-29
申请号:EP20714054.2
申请日:2020-02-21
申请人: Xencor, Inc.
发明人: MOORE, Gregory , VARMA, Rajat , KIM, Yoon, Kyung , RASHID, Rumana , CHANG, Eric , NISTHAL, Alex , DIAZ, Juan , BERNETT, Matthew , HEDVAT, Michael
IPC分类号: C07K14/54
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公开(公告)号:EP3526241A1
公开(公告)日:2019-08-21
申请号:EP17804322.0
申请日:2017-10-16
申请人: Xencor, Inc.
IPC分类号: C07K14/54 , C07K14/715 , C07K19/00
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7.RAPID CLEARANCE OF ANTIGEN COMPLEXES USING NOVEL ANTIBODIES 审中-公开
标题翻译: SCHNELLE BESEITIGUNG VON ANTIGENKOMPLEXEN UNTER VERWENDUNG NEUARTIGERANTIKÖRPER公开(公告)号:EP2945969A1
公开(公告)日:2015-11-25
申请号:EP14702177.8
申请日:2014-01-15
申请人: Xencor, Inc.
IPC分类号: C07K16/42 , C07K14/435 , C07K14/47
CPC分类号: C07K16/2878 , A61K38/17 , A61K38/1709 , A61K38/177 , A61K38/1774 , A61K39/395 , A61K39/3955 , A61K2039/505 , A61K2039/54 , C07K14/435 , C07K16/1027 , C07K16/18 , C07K16/2803 , C07K16/4291 , C07K16/46 , C07K2317/24 , C07K2317/30 , C07K2317/52 , C07K2317/72 , C07K2317/732 , C07K2317/76 , C07K2317/77 , C07K2317/92 , C07K2319/30 , C07K2319/32
摘要: The present invention relates to rapid clearance molecules that bind target antigens and FcγRIIb with increased affinity as compared to parent molecules, the compositions being capable of causing accelerated clearance of such antigens. Such compositions are useful for treating a variety of disorders, including allergic diseases, atherosclerosis, and a variety of other conditions.
摘要翻译: 本发明涉及与亲本分子相比具有增加的亲和力的结合靶抗原的快速清除分子和FcγRIIb,所述组合物能够促进这些抗原的加速清除。 这些组合物可用于治疗多种疾病,包括过敏性疾病,动脉粥样硬化和各种其他病症。
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公开(公告)号:EP4257613A3
公开(公告)日:2023-12-13
申请号:EP23172675.3
申请日:2017-06-14
申请人: Xencor, Inc.
发明人: BERNETT, Matthew , MOORE, Gregory , DESJARLAIS, John , HEDVAT, Michael , BONZON, Christine , NISTHAL, Alex , MUCHHAL, Umesh, S.
摘要: The present invention is directed to bispecific, heterodimeric checkpoint antibodies.
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公开(公告)号:EP4059514A1
公开(公告)日:2022-09-21
申请号:EP22155270.6
申请日:2016-04-28
申请人: Xencor, Inc.
发明人: MOORE, Gregory , DESLARLAIS, John , BERNETT, Matthew , CHU, Seung , RASHID, Rumana , MUCHHAL, Umesh , LEE, Sung-Hyung
摘要: The present invention is directed to novel heterodimeric antibodies.
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