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公开(公告)号:EP3928788A1
公开(公告)日:2021-12-29
申请号:EP21173790.3
申请日:2015-11-25
申请人: Xencor, Inc.
发明人: MOORE, Gregory , DESJARLAIS, John , BERNETT, Matthew , CHU, Seung , RASHID, Rumana , MUCHHAL, Umesh , LEE, Sung-Hyung
摘要: The present invention is directed to novel heterodimeric antibodies.
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公开(公告)号:EP4059514A1
公开(公告)日:2022-09-21
申请号:EP22155270.6
申请日:2016-04-28
申请人: Xencor, Inc.
发明人: MOORE, Gregory , DESLARLAIS, John , BERNETT, Matthew , CHU, Seung , RASHID, Rumana , MUCHHAL, Umesh , LEE, Sung-Hyung
摘要: The present invention is directed to novel heterodimeric antibodies.
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公开(公告)号:EP3223907A2
公开(公告)日:2017-10-04
申请号:EP15816291.7
申请日:2015-11-25
申请人: Xencor, Inc.
发明人: MOORE, Gregory , DESJARLAIS, John , BERNETT, Matthew , CHU, Seung , RASHID, Rumana , MUCHHAL, Umesh
CPC分类号: C07K16/40 , A61K2039/505 , C07K16/18 , C07K16/2809 , C07K16/2896 , C07K16/3061 , C07K2317/24 , C07K2317/31 , C07K2317/33 , C07K2317/522 , C07K2317/524 , C07K2317/526 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/622 , C07K2317/64 , C07K2317/73 , C07K2317/92
摘要: The present invention is directed to heterodimeric antibodies that bind CD3 and CD38.
摘要翻译: 本发明涉及结合CD3和CD38的异二聚体抗体。
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公开(公告)号:EP1636256A2
公开(公告)日:2006-03-22
申请号:EP04785771.9
申请日:2004-03-30
申请人: Xencor, Inc.
发明人: AGUINALDO, Anna Marie , BEYNA, Amelia, Joy , CHO, Ho, Sung , DESJARLAIS, John, Rudolph , MARSHALL, Shannon, Alicia , MUCHHAL, Umesh , VILLEGAS, Michael, Francis, Aquino , ZHUKOVSKY, Eugene , QUESENBERRY, Michael, Stephen
IPC分类号: C07K14/415 , C07K14/565 , C07K14/56
CPC分类号: C07K14/565 , C07K14/555 , C07K14/56
摘要: This invention relates to interferon variants with improved properties and methods for their use.
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公开(公告)号:EP1581631A2
公开(公告)日:2005-10-05
申请号:EP03799328.4
申请日:2003-09-30
申请人: Xencor Inc.
发明人: AGUINALDO, Anna, Marie , BEYNA, Amelia, Joy , DESJARLAIS, John, Rudolph , MARSHALL, Shannon, Alicia , MUCHHAL, Umesh , VILLEGAS, Michael Francis Aquino , ZHUKOVSKY, Eugene , CHO, Ho Sung
IPC分类号: C12N1/00
CPC分类号: C07K14/56 , A61K38/00 , C07K14/555 , C07K14/565
摘要: The invention relates to interferon variants with improved properties and methods for their use.
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公开(公告)号:EP3380196A1
公开(公告)日:2018-10-03
申请号:EP16808889.6
申请日:2016-11-23
申请人: Amgen Inc. , Xencor, Inc.
发明人: STEVENS, Jennitte, Leann , BALAZS, Mercedesz , NOLAN-STEVAUX, Olivier , MOORE, Gregory , DESJARLAIS, John , BERNETT, Matthew, J. , CHU, Seung, Y. , RASHID, Rumana , MUCHHAL, Umesh
CPC分类号: C07K16/40 , A61K2039/505 , C07K16/18 , C07K16/2809 , C07K16/2896 , C07K16/3061 , C07K2317/24 , C07K2317/31 , C07K2317/33 , C07K2317/522 , C07K2317/524 , C07K2317/526 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/622 , C07K2317/64 , C07K2317/73 , C07K2317/92
摘要: The present invention is directed to heterodimeric antibodies that bind CD3 and CD38.
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公开(公告)号:EP3107935A2
公开(公告)日:2016-12-28
申请号:EP15708398.1
申请日:2015-02-19
申请人: ALLERGAN, INC. , Xencor, Inc.
发明人: BACIU, Peter C. , LIANG, Yanbin , GUU, Jason , BERNETT, Matthew , MUCHHAL, Umesh , DESJARLAIS, John
IPC分类号: C07K16/18 , A61K39/395
摘要: The present disclosure relates to antibodies and polynucleotides encoding the same, that may be used to prevent, control, or reduce the activity of the complement pathway. In addition, the disclosure is directed to compositions and methods for diagnosing and treating diseases mediated by or involving complement C5. Specifically, the disclosure is related to C5 antibodies.
摘要翻译: 本公开涉及编码该抗体和多核苷酸的抗体和多核苷酸,其可用于预防,控制或降低补体途径的活性。 此外,本公开涉及用于诊断和治疗由补体C5介导或涉及补体C5的疾病的组合物和方法。 具体地,本公开涉及C5抗体。
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8.PROTEIN BASED TNF-ALPHA VARIANTS FOR THE TREATMENT OF TNF-ALPHA RELATED DISORDERS 有权
标题翻译: TNF-ALPHA-变体,蛋白基料用于疾病治疗与TNF-ALPHA公开(公告)号:EP1578988B1
公开(公告)日:2012-11-07
申请号:EP02801645.9
申请日:2002-09-30
申请人: Xencor, Inc.
发明人: DAHIYAT, Bassil, I. , DESJARLAIS, John, R. , FILIKOV, Anton , MUCHHAL, Umesh , TANSEY, Malu , ZALEVSKY, Jonathan
IPC分类号: C07K14/525
CPC分类号: A61K38/191 , C07K14/525
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公开(公告)号:EP3706793A1
公开(公告)日:2020-09-16
申请号:EP18815837.2
申请日:2018-11-08
申请人: Xencor, Inc.
发明人: BERNETT, Matthew, J. , DESJARLAIS, John , MOORE, Gregory , HEDVAT, Michael , BONZON, Christine , NISTHAL, Alex , MUCHHAL, Umesh
IPC分类号: A61K39/395 , C07K16/28 , A61P35/00 , A61K39/00
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公开(公告)号:EP3107935B1
公开(公告)日:2020-06-24
申请号:EP15708398.1
申请日:2015-02-19
申请人: ALLERGAN, INC. , Xencor, Inc.
发明人: BACIU, Peter C. , LIANG, Yanbin , GUU, Jason , BERNETT, Matthew , MUCHHAL, Umesh , DESJARLAIS, John
IPC分类号: C07K16/18 , A61K39/395
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