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1.发明公开COMBINATION THERAPY FOR PROSTATE CANCER USING BOTANICAL COMPOSITIONS AND BICALUTAMIDE 审中-公开综合疗法治疗前列腺癌蔬菜成分和比卡鲁胺
公开(公告)号：EP2635127A1
公开(公告)日：2013-09-11
申请号：EP11838925.3
申请日：2011-11-04
发明人： DAO, James , GAO, Allen, Chuan , GERWICK, William , GERWICK, Lena , JORDAN, MaryAnn , MIKOVITS, Judy , OKOUNEVA, Tatiana , OROUDJEV, Emin
IPC分类号： A01N65/00
CPC分类号： A61K36/074 , A61K9/2086 , A61K31/277 , A61K36/537 , A61K36/539 , A61K38/24 , A61K2300/00
摘要： Botanical compositions comprising non-alcoholic organic extracts of Ganoderma lucidum, Salvia miltiorrhiza, and Scutellaria barbata for use in conjunction with bicalutamide therapy fpr cancer therapy, are provided. Methods for treatment or therapy of prostate cancer in a human is provided, the method comprising: administering an effective amount of a botanical composition that is effective for reducing androgen receptor protein expression; and administering concurrently an effective amount of a compound having anti-androgen activity, wherein the concurrent administration of the compound and the botanical composition achieves a therapeutic effect that is more effective than either agent alone.
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公开(公告)号：EP2635127B1
公开(公告)日：2018-10-17
申请号：EP11838925.3
申请日：2011-11-04
发明人： DAO, James , GAO, Allen, Chuan , GERWICK, William , GERWICK, Lena , JORDAN, MaryAnn , MIKOVITS, Judy , OKOUNEVA, Tatiana , OROUDJEV, Emin , DAO, Jeffrey
IPC分类号： A61K36/074 , A61K36/537 , A61K36/539 , A61K31/165
CPC分类号： A61K36/074 , A61K9/2086 , A61K31/277 , A61K36/537 , A61K36/539 , A61K38/24 , A61K2300/00
摘要： Botanical compositions comprising non-alcoholic organic extracts of Ganoderma lucidum, Salvia miltiorrhiza, and Scutellaria barbata for use in conjunction with bicalutamide therapy fpr cancer therapy, are provided. Methods for treatment or therapy of prostate cancer in a human is provided, the method comprising: administering an effective amount of a botanical composition that is effective for reducing androgen receptor protein expression; and administering concurrently an effective amount of a compound having anti-androgen activity, wherein the concurrent administration of the compound and the botanical composition achieves a therapeutic effect that is more effective than either agent alone.
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