公开(公告)号：EP2635127A1

公开(公告)日：2013-09-11

申请号：EP11838925.3

申请日：2011-11-04

申请人： Genyous Biomed International ,  Dao, Jeffrey

发明人： DAO, James ,  GAO, Allen, Chuan ,  GERWICK, William ,  GERWICK, Lena ,  JORDAN, MaryAnn ,  MIKOVITS, Judy ,  OKOUNEVA, Tatiana ,  OROUDJEV, Emin

IPC分类号： A01N65/00

CPC分类号： A61K36/074 ,  A61K9/2086 ,  A61K31/277 ,  A61K36/537 ,  A61K36/539 ,  A61K38/24 ,  A61K2300/00

摘要： Botanical compositions comprising non-alcoholic organic extracts of Ganoderma lucidum, Salvia miltiorrhiza, and Scutellaria barbata for use in conjunction with bicalutamide therapy fpr cancer therapy, are provided. Methods for treatment or therapy of prostate cancer in a human is provided, the method comprising: administering an effective amount of a botanical composition that is effective for reducing androgen receptor protein expression; and administering concurrently an effective amount of a compound having anti-androgen activity, wherein the concurrent administration of the compound and the botanical composition achieves a therapeutic effect that is more effective than either agent alone.

公开(公告)号：EP3003490B1

公开(公告)日：2019-11-13

申请号：EP14807920.5

申请日：2014-06-03

申请人： Genyous Biomed International

发明人： DAO, James ,  DAO, Jeffery ,  GERWICK, William ,  GERWICK, Lena ,  JORDAN, MaryAnn ,  WILSON, Leslie

IPC分类号： A61P35/00 ,  A61K36/074 ,  A61K31/337 ,  A61K36/537 ,  A61K36/539

公开(公告)号：EP2635127B1

公开(公告)日：2018-10-17

申请号：EP11838925.3

申请日：2011-11-04

申请人： Genyous Biomed International

发明人： DAO, James ,  GAO, Allen, Chuan ,  GERWICK, William ,  GERWICK, Lena ,  JORDAN, MaryAnn ,  MIKOVITS, Judy ,  OKOUNEVA, Tatiana ,  OROUDJEV, Emin ,  DAO, Jeffrey

IPC分类号： A61K36/074 ,  A61K36/537 ,  A61K36/539 ,  A61K31/165

CPC分类号： A61K36/074 ,  A61K9/2086 ,  A61K31/277 ,  A61K36/537 ,  A61K36/539 ,  A61K38/24 ,  A61K2300/00

摘要： Botanical compositions comprising non-alcoholic organic extracts of Ganoderma lucidum, Salvia miltiorrhiza, and Scutellaria barbata for use in conjunction with bicalutamide therapy fpr cancer therapy, are provided. Methods for treatment or therapy of prostate cancer in a human is provided, the method comprising: administering an effective amount of a botanical composition that is effective for reducing androgen receptor protein expression; and administering concurrently an effective amount of a compound having anti-androgen activity, wherein the concurrent administration of the compound and the botanical composition achieves a therapeutic effect that is more effective than either agent alone.

公开(公告)号：EP3003490A1

公开(公告)日：2016-04-13

申请号：EP14807920.5

申请日：2014-06-03

申请人： Genyous Biomed International

发明人： DAO, James ,  DAO, Jeffery ,  GERWICK, William ,  GERWICK, Lena ,  JORDAN, MaryAnn ,  WILSON, Leslie

IPC分类号： A61P35/00 ,  A61K36/074

摘要： Methods for using botanical compositions comprising administration of non-alcoholic organic extracts of Ganoderma lucidum, Salvia miltiorrhiza, and Scutellaria barbata in conjunction with docetaxel for cancer therapy, are provided. Method for treatment or therapy of prostate cancer in a human is provided, the method comprising: administering an effective amount of the botanical composition during a period of administering concurrently an effective amount of docetaxel, wherein the concurrent administration of the docetaxel and the botanical composition achieves a therapeutic effect that is more effective than either agent alone.