专利检索 ap:("Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts, Universitätsmedizin" OR "Georg-August-Universität Göttingen") AND inv:"VOSS, Edgar" 第 1 页

1.

发明公开
AZOLO COMPOUNDS FOR TREATMENT OF FIBROTIC DISEASES 审中-实审

公开(公告)号：EP4404931A1

公开(公告)日：2024-07-31

申请号：EP23735593.8

申请日：2023-05-19

申请人： Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts, Universitätsmedizin , Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts

发明人： TIETZE, Lutz Friedjahn , VOSS, Edgar , MOTHUKU, Shyam Sundar , ZEISBERG, Michael , HASENFUSS, Gerd , NYAMSUREN, Gunsmaa

IPC分类号： A61K31/5025 , A61P1/00 , A61P9/00 , A61P11/00 , A61P13/12

CPC分类号： A61K31/5025 , A61P9/00 , A61P1/00 , A61P11/00 , A61P13/12

2.

发明公开
AZOLO COMPOUNDS FOR TREATMENT OF FIBROTIC DISEASES 审中-公开

公开(公告)号：EP4279074A1

公开(公告)日：2023-11-22

申请号：EP22174346.1

申请日：2022-05-19

申请人： Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts, Universitätsmedizin , Georg-August-Universität Göttingen

发明人： TIETZE, Lutz Friedjahn , MOTHUKU, Shyam Sundar , ZEISBERG, Michael , HASENFUSS, Gerd , NYAMSUREN, Gunsmaa , VOSS, Edgar

IPC分类号： A61K31/5025 , A61P1/00 , A61P9/00 , A61P11/00 , A61P13/12

摘要： The present invention relates to an azolo compound of Formula I

for use in the treatment of fibrosis, wherein the azolo compounds normalizes collagen I mRNA-levels of TGFβ-activated fibroblasts and reverses collagen production to the normal levels that are seen in fibroblasts that are not stimulated.