公开(公告)号：EP4282482A2

公开(公告)日：2023-11-29

申请号：EP23197008.8

申请日：2008-03-26

申请人： Gilead Sciences, Inc.

发明人： SOFIA, Michael, Joseph ,  DU, Jinfa ,  WANG, Peiyuan ,  NAGARATHNAM, Dhanapalan

IPC分类号： A61P31/00

摘要： Disclosed herein are phosphoramidate prodrugs of nucleoside derivatives for the treatment of viral infections in mammals, which is a compound, its stereoisomer, salt (acid or basic addition salt), hydrate, solvate, or crystalline form thereof, represented by the following structure:

Also disclosed are methods of treatment, uses, and processes for preparing each of which utilize the compound represented by formula I.

公开(公告)号：EP4282482A3

公开(公告)日：2024-01-17

申请号：EP23197008.8

申请日：2008-03-26

申请人： Gilead Sciences, Inc.

发明人： SOFIA, Michael, Joseph ,  DU, Jinfa ,  WANG, Peiyuan ,  NAGARATHNAM, Dhanapalan

IPC分类号： C07H19/10 ,  A61K31/7072 ,  A61P31/00

摘要： Disclosed herein are phosphoramidate prodrugs of nucleoside derivatives for the treatment of viral infections in mammals, which is a compound, its stereoisomer, salt (acid or basic addition salt), hydrate, solvate, or crystalline form thereof, represented by the following structure:

Also disclosed are methods of treatment, uses, and processes for preparing each of which utilize the compound represented by formula I.