NOVEL COMPOUNDS
    2.
    发明公开
    NOVEL COMPOUNDS 审中-公开
    新化合物

    公开(公告)号:EP2164837A1

    公开(公告)日:2010-03-24

    申请号:EP08760915.2

    申请日:2008-06-12

    CPC分类号: C07D295/185

    摘要: The invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof for treating diseases and conditions mediated by positive allosteric modulation of the G- protein coupled metabotropic subtype 5 receptor (mGluR5), such as neurological and psychiatric disorders, for example schizophrenia. In addition, the invention relates to compositions containing the derivatives and processes for their preparation.

    摘要翻译: 本发明提供了式(I)化合物或其药学上可接受的盐,用于治疗由G-蛋白偶联的代谢型亚型5受体(mGluR5)的正变构调节介导的疾病和病症,例如神经病学和精神病学疾病,例如精神分裂症 。 此外,本发明涉及含有该衍生物的组合物及其制备方法。