专利检索 ap:("Guangzhou Baiyunshan Pharmaceutical Holdings Co., Ltd. Baiyunshan Pharmaceutical General Factory" OR "Medshine Discovery Inc.") AND inv:"FU, Zhifei" 第 1 页

1.

发明公开
NITROGEN-CONTAINING SPIRO DERIVATIVE AS RET INHIBITOR 审中-公开

公开(公告)号：EP3950688A1

公开(公告)日：2022-02-09

申请号：EP20782749.4

申请日：2020-04-03

申请人： Guangzhou Baiyunshan Pharmaceutical Holdings Co., Ltd. Baiyunshan Pharmaceutical General Factory , Medshine Discovery Inc.

发明人： WANG, Jiansong , FU, Zhifei , LUO, Zhibo , LUO, Miaorong , ZHANG, Yang , CAI, Yalei , ZHU, Wu , LI, Jian , CHEN, Shuhui , BAO, Yingxia , WANG, Wei , XIE, Zhoufan

IPC分类号： C07D471/10 , C07D401/14 , C07D403/14 , A61K31/506 , A61P35/00

摘要： Disclosed are a series of compounds with a nitrogen-containing spiro structure and an application thereof in the preparation of an RET kinase inhibitor. Specifically, disclosed is a compound as shown in formula (II) or a pharmaceutically acceptable salt thereof.

2.

发明公开
CRYSTAL FORMS OF PYRIDOPYRAZOLE COMPOUNDS AND PREPARATION METHOD THEREFOR 审中-公开

公开(公告)号：EP4194455A1

公开(公告)日：2023-06-14

申请号：EP21874399.5

申请日：2021-09-26

申请人： Guangzhou Baiyunshan Pharmaceutical Holdings Co., Ltd. Baiyunshan Pharmaceutical General Factory

发明人： WANG, Jiansong , FU, Zhifei , LUO, Zhibo , LUO, Miaorong , ZHANG, Yang , LI, Jian , CHEN, Shuhui , BAO, Yingxia , WANG, Wei , XIE, Zhoufan

IPC分类号： C07D471/04 , A61K31/437 , A61P35/00

摘要： Provided are crystal forms of compounds represented by formula(II)-formula (VIII) and formula (I)-fbrmula (VIII-1), a preparation method therefor and an application of the compounds and crystal forms in the preparation of a drug for treating a related disease.

3.

发明公开
DEUTERATED THIENOPYRIDINE COMPOUND 审中-公开

公开(公告)号：EP4089095A1

公开(公告)日：2022-11-16

申请号：EP21738457.7

申请日：2021-01-07

申请人： Medshine Discovery Inc.

发明人： FU, Zhifei , LUO, Miaorong , ZHANG, Yang , LI, Jian , CHEN, Shuhui

IPC分类号： C07D495/04 , A61K31/4365 , A61K31/444 , A61P35/00

摘要： Disclosed is a deuterated thienopyridine compound. Specifically disclosed are a compound represented by formula (I) and a pharmaceutically acceptable salt thereof.

4.

发明公开
PYRAZOLE-1(2H)-PHTHALAZINONE COMPOUND AND APPLICATION THEREOF 审中-公开

公开(公告)号：EP4458812A1

公开(公告)日：2024-11-06

申请号：EP22914793.9

申请日：2022-12-27

申请人： Medshine Discovery Inc.

发明人： FU, Zhifei , LUO, Miaorong , YU, Chenxi , ZHOU, Kai , GAO, Na , ZHANG, Yang , LI, Jian , CHEN, Shuhui

IPC分类号： C07D237/32 , C07D403/10 , C07D487/00 , A61K31/502 , A61P35/00

摘要： Provided are a pyrazole-1(2H)-phthalazinone compound and an application thereof as a PRMTS. MTA complex inhibitor in the preparation of a drug for treating related diseases.