摘要:
The present invention provides a method of inducing or enhancing an immune response to polysaccharides or other T cell-independent antigen by the coadministration of the antigen with bacterial lipoproteins (including covalent attachment of the antigen and lipoproteins). In a preferred embodiment, the lipoprotein of the invention is lipoprotein D.
摘要:
A multi-valent vaccine composition is described comprising a whole-cell pertussis component, tetanus toxoid, diphtheria toxoid, and a low dose of a conjugate of the capsular polysaccharide of H. influenzae b.
摘要:
A detoxified B. pertussis toxin or antigenic preparation is described, which is characterized by stability to reversion to toxicity upon storage at 4-8 °C and at temperatures above 23 °C. Also provided are methods for producing detoxified pertussis toxin and vaccines containing same.
摘要:
A multi-valent vaccine composition is described comprising a whole-cell pertussis component, tetanus toxoid, diphtheria toxoid, and a low dose of a conjugate of the capsular polysaccharide of H. influenzae b.
摘要:
On décrit une toxine de B. pertussis détoxifiée ou une préparation antigénique caractérisée par une stabilité empêchant la réversion à la toxicité lors du stockage à 4-8 °C et à des températures supérieures à 23 °C. On présente également des procédés permettant d'obtenir la toxine de pertussis détoxifiée et des vaccins la contenant.
摘要:
A multi-valent vaccine composition is described comprising a whole-cell pertussis component, tetanus toxoid, diphtheria toxoid, and a low dose of a conjugate of the capsular polysaccharide of H. influenzae b.
摘要:
The present invention relates to the field of bacterial polysaccharide antigen vaccines. Streptococcus pneumoniae, and optionally a Th1-inducing adjuvant.