-
公开(公告)号：EP1039930A2
公开(公告)日：2000-10-04
申请号：EP98966705.0
申请日：1998-12-18
IPC分类号： A61K39/39
CPC分类号： A61K39/12 , A61K38/00 , A61K39/02 , A61K39/092 , A61K39/39 , A61K2039/55561 , A61K2039/585 , A61K2039/6068 , C07K14/005 , C07K2319/00 , C12N2710/20022 , C12N2710/20034 , Y02A50/412 , Y02A50/472
摘要： The present invention provides Human Papilloma Virus (HPV) fusion proteins, linked to an immunological fusion partner that provides T helper epiptopes to the HPV antigen. Vaccine formulations are provided that are useful in the treatment or Prophylaxis of HPV induced tumours.
-
公开(公告)号：EP0820304B1
公开(公告)日：2000-06-21
申请号：EP96912001.3
申请日：1996-04-01
发明人： PRIEELS, Jean-Paul , SLAOUI, Moncef Mohamed , MAISONNEUVE, Jean-François, Uni. des Sciences , VERLANT, Vincent, Uni. des Sciences
IPC分类号： A61K39/118 , A61K39/39
CPC分类号： C07K14/295 , A61K39/00 , A61K39/118 , A61K39/39 , A61K2039/55555 , A61K2039/55572 , A61K2039/55577
摘要： A novel vaccine is presented for the prevention of Chlamydia infections utilising the outer membrane protein and two immunostimulants, 3D-MPL and QS21.
-
公开(公告)号：EP0820304A1
公开(公告)日：1998-01-28
申请号：EP96912001.0
申请日：1996-04-01
发明人： PRIEELS, Jean-Paul , SLAOUI, Moncef Mohamed , MAISONNEUVE, Jean-François, Uni. des Sciences , VERLANT, Vincent, Uni. des Sciences
CPC分类号： C07K14/295 , A61K39/00 , A61K39/118 , A61K39/39 , A61K2039/55555 , A61K2039/55572 , A61K2039/55577
摘要： A novel vaccine is presented for the prevention of Chlamydia infections utilising the outer membrane protein and two immunostimulants, 3D-MPL and QS21.
-
公开(公告)号：EP0671948B1
公开(公告)日：1997-08-13
申请号：EP93912990.4
申请日：1993-06-15
发明人： PRIEELS, Jean-Paul , GARCON-JOHNSON, Nathalie Marie-Josephe Claude , SLAOUI, Moncef , PALA, Pietro
CPC分类号： A61K39/292 , A61K39/015 , A61K39/12 , A61K39/245 , A61K39/29 , A61K39/39 , A61K2039/55505 , A61K2039/55572 , A61K2039/55577 , A61K2039/57 , C12N2710/16634 , C12N2730/10134 , Y02A50/412 , Y02A50/464
摘要： The present invention provides vaccine compositions comprising 3 De-O-acylated monophosphoryl lipid A and QS21. The vaccines compositions are potent inducers of CTL and gamma IFN responses.
-
5.发明授权HERPES SIMPLEX VACCINE COMPRISING HSV GLYCOPROTEIN GD AND 3 DEACYLATED MONOPHOSPHORYL LIPID A 失效单纯疱疹疫苗，THE HSV糖蛋白gD和3-脱酰基单磷酰脂质A含有。
公开(公告)号：EP0576478B1
公开(公告)日：1995-10-18
申请号：EP92906441.8
申请日：1992-03-17
发明人： FRANCOTTE, Myriam , PRIEELS, Jean-Paul , SLAOUI, Moncef , GARCON-JOHNSON, Nathalie, Marie-Josephe, Claude
IPC分类号： A61K39/245
CPC分类号： A61K39/245 , A61K39/12 , A61K2039/541 , A61K2039/545 , A61K2039/55505 , A61K2039/55566 , A61K2039/55572 , A61K2039/57 , C12N2710/16634
摘要： Novel herpes simplex (HSV) vaccine formulations are provided. These comprise HSV glycoprotein gD or immunological fragments in conjunction with 3 Deacylated monophosphoryl lipid A.
-
公开(公告)号：EP0671948A1
公开(公告)日：1995-09-20
申请号：EP93912990.0
申请日：1993-06-15
发明人： PRIEELS, Jean-Paul , GARCON-JOHNSON, Nathalie Marie-Josephe Claude , SLAOUI, Moncef , PALA, Pietro
CPC分类号： A61K39/292 , A61K39/015 , A61K39/12 , A61K39/245 , A61K39/29 , A61K39/39 , A61K2039/55505 , A61K2039/55572 , A61K2039/55577 , A61K2039/57 , C12N2710/16634 , C12N2730/10134 , Y02A50/412 , Y02A50/464
摘要： The present invention provides vaccine compositions comprising 3 De-O-acylated monophosphoryl lipid A and QS21. The vaccines compositions are potent inducers of CTL and gamma IFN responses.
-
公开(公告)号：EP0563091A1
公开(公告)日：1993-10-06
申请号：EP92900495.0
申请日：1991-12-16
CPC分类号： C07K14/005 , C07K19/00 , C12N2730/10122
摘要： Nouveaux antigènes utiles dans les formulations vaccinales destinées au traitement prophylactique d'une série de maladies infectieuses. Les antigènes sont constitués d'un polypeptide hybride dont l'une des parties est l'antigène S du virus de l'hépatite B, et dont l'autre partie est un antigène hétérologue tel que le gD de HSV. Les deux antigènes sont reliés l'un à l'autre par des segments intercalaires chimiques par l'intermédiaire d'un groupe sulfydryle natif présent à la surface de l'antigène S.
-
公开(公告)号：EP1163000A2
公开(公告)日：2001-12-19
申请号：EP00912626.9
申请日：2000-03-17
发明人： CAPIAU, Carine , DESCHAMPS, Marguerite , DESMONS, Pierre, Michel , LAFERRIERE, Craig, Antony, Joseph , POOLMAN, Jan , PRIEELS, Jean-Paul
IPC分类号： A61K39/385 , A61K39/39 , A61K39/02 , A61K39/005 , A61K39/116 , A61P31/04
CPC分类号： A61K47/4833 , A61K39/092 , A61K39/095 , A61K39/102 , A61K39/12 , A61K39/155 , A61K47/646 , A61K2039/55505 , A61K2039/55572 , A61K2039/6037 , A61K2039/6068 , A61K2039/6075 , A61K2039/70 , Y02A50/414 , Y02A50/484 , Y10S424/831
摘要： The present invention relates to the field of bacterial polysaccharide antigen vaccines. Streptococcus pneumoniae, and optionally a Th1-inducing adjuvant.
-
9.发明授权HERPES SIMPLEX VACCINE COMPRISING HSV GLYCOPROTEIN GD AND 3 DEACYLATED MONOPHOSPHORYL LIPID A 失效单纯疱疹疫苗的HSV糖蛋白gD和3-脱酰基单磷酰脂质A包含
公开(公告)号：EP0576478B2
公开(公告)日：2001-04-18
申请号：EP92906441.8
申请日：1992-03-17
发明人： FRANCOTTE, Myriam , PRIEELS, Jean-Paul , SLAOUI, Moncef , GARCON-JOHNSON, Nathalie, Marie-Josephe, Claude
IPC分类号： A61K39/245
CPC分类号： A61K39/245 , A61K39/12 , A61K2039/541 , A61K2039/545 , A61K2039/55505 , A61K2039/55566 , A61K2039/55572 , A61K2039/57 , C12N2710/16634
摘要： Novel herpes simplex (HSV) vaccine formulations are provided. These comprise HSV glycoprotein gD or immunological fragments in conjunction with 3 Deacylated monophosphoryl lipid A.
-
10.发明公开INDUCTION AND ENHANCEMENT OF THE IMMUNE RESPONSE TO POLYSACCHARIDES WITH BACTERIAL LIPOPROTEINS 失效诱发和提高免疫ANTWORTES多糖BY BACTERIALEN脂蛋白
公开(公告)号：EP0824360A1
公开(公告)日：1998-02-25
申请号：EP96911776.0
申请日：1996-04-16
申请人： HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE , SMITHKLINE BEECHAM BIOLOGICALS S.A.
CPC分类号： C07K14/285 , A61K39/385 , A61K2039/55516 , A61K2039/55594 , A61K2039/6068 , Y02A50/482
摘要： The present invention provides a method of inducing or enhancing an immune response to polysaccharides or other T cell-independent antigen by the coadministration of the antigen with bacterial lipoproteins (including covalent attachment of the antigen and lipoproteins). In a preferred embodiment, the lipoprotein of the invention is lipoprotein D.
-
-
-
-
-
-
-
-
-
搜索结果
11 条记录 (耗时 0.015 秒)
