公开(公告)号：EP0734281A4

公开(公告)日：1996-11-20

申请号：EP95937465

申请日：1995-10-19

申请人： HEWLETT PACKARD CO

发明人： KALTENBACH PATRICK ,  SWEDBERG SALLY A ,  WITT KLAUS E ,  BEK FRITZ ,  MITTELSTADT LAURIE S

IPC分类号： B01D15/08 ,  B01L3/00 ,  B01L7/00 ,  B29C65/02 ,  B81B1/00 ,  B81C1/00 ,  G01N27/447 ,  G01N30/02 ,  G01N30/28 ,  G01N30/30 ,  G01N30/60 ,  G01N37/00

CPC分类号： G01N30/6095 ,  B01L3/502707 ,  B01L3/502715 ,  B01L3/5055 ,  B01L7/54 ,  B01L2200/025 ,  B01L2200/0689 ,  B01L2200/10 ,  B01L2200/12 ,  B01L2300/0816 ,  B01L2300/087 ,  B01L2300/0874 ,  B01L2300/0887 ,  B01L2300/1822 ,  B01L2400/0415 ,  B29C65/02 ,  B29C66/54 ,  B29C66/549 ,  B29L2031/756 ,  G01N27/44704 ,  G01N27/44708 ,  G01N27/44721 ,  G01N27/44773 ,  G01N27/44791 ,  G01N30/02 ,  G01N30/60 ,  G01N30/6047 ,  G01N30/6052 ,  G01N30/606 ,  G01N2030/285 ,  G01N2030/3007 ,  G01N2030/3015 ,  G01N2030/303 ,  Y10T156/1064 ,  G01N2030/0035

摘要： Miniaturized planar column devices (2) are described for use in liquid phase analysis, the devices comprising microstructures fabricated by laser ablation in a variety of support substrates (4). Devices formed according to the invention include associated laser-ablated features required for function, such as analyte detection device (34, 36) and fluid communication device (10). Miniaturized columns constructed under the invention find use in any analysis system performed on either small and/or macromolecular solutes in the liquid phase and may employ chromatographic, electrophoretic, electromatographic separation device, or any combination thereof.

公开(公告)号：EP0734282A4

公开(公告)日：1996-11-20

申请号：EP95937504

申请日：1995-10-16

申请人： HEWLETT PACKARD CO

发明人： KALTENBACH PATRICK ,  SWEDBERG SALLY A ,  WITT KLAUS E ,  BEK FRITZ ,  MITTELSTADT LAURIE S

IPC分类号： B01D15/08 ,  B01L3/00 ,  B01L7/00 ,  B29C65/02 ,  B81B1/00 ,  B81C1/00 ,  G01N27/447 ,  G01N30/02 ,  G01N30/28 ,  G01N30/30 ,  G01N30/60 ,  G01N37/00

CPC分类号： G01N30/6095 ,  B01L3/502707 ,  B01L3/502715 ,  B01L3/5055 ,  B01L7/54 ,  B01L2200/025 ,  B01L2200/0689 ,  B01L2200/10 ,  B01L2200/12 ,  B01L2300/0816 ,  B01L2300/087 ,  B01L2300/0874 ,  B01L2300/0887 ,  B01L2300/1822 ,  B01L2400/0415 ,  B29C65/02 ,  B29C66/54 ,  B29C66/549 ,  B29L2031/756 ,  G01N27/44704 ,  G01N27/44708 ,  G01N27/44721 ,  G01N27/44773 ,  G01N27/44791 ,  G01N30/02 ,  G01N30/60 ,  G01N30/6047 ,  G01N30/6052 ,  G01N30/606 ,  G01N2030/285 ,  G01N2030/3007 ,  G01N2030/3015 ,  G01N2030/303 ,  Y10T156/1064 ,  G01N2030/0035

摘要： Miniaturized planar column devices (2) for use in liquid phase separation apparatus are described. The devices include microstructures that have been fabricated by laser ablation in a variety of novel support substrates. Devices formed according to the methods of the invention include associated laser-ablated features required for function, such as on-device reservoirs (16) or makeup flos compartments, analyte detection means and sample injection means. The miniaturized columns can be used in an apparatus intended for analysis of either small and/or macromolecular solutes in the liquid phase which employs chromatographic electrophoretic, electrochromatographic separation means. The apparatus can include a variety of optional injection means, manifolds, keeper means, post column collection means, and combinations thereof.