公开(公告)号：EP1429835B1

公开(公告)日：2006-06-21

申请号：EP02731520.9

申请日：2002-04-24

申请人： Hewlett-Packard Company

发明人： PICKUP, Ray, L. ,  LO, Clement, C. ,  NOONAN, William, D.

IPC分类号： A61M35/00 ,  A61M5/30 ,  A61K9/00 ,  A61M37/00 ,  A01K11/00 ,  A61M11/00 ,  A61D7/00

CPC分类号： B41J2/16535 ,  A01K11/005 ,  A01K13/003 ,  A61M5/14248 ,  A61M31/002 ,  A61M35/003 ,  A61M37/00 ,  A61M37/0084 ,  B41J2/16505 ,  B41J3/36 ,  B41J3/407

摘要： Bioactive agents are cutaneously delivered by a thermal or piezoelectric jet dispenser (30). The dispenser (30) propels precise volumes of droplets toward the skin (24), where they exert a local or topical effect, or move through the skin (24) for transdermal systemic delivery. Drugs are either delivered directly to the skin (24), or are introduced into a transdermal patch (25). The dispenser (30) can be used to resupply a transdermal patch (25) with drug instead of replacing the patch. A controller (100, 220) in the dispenser is capable of accurately controlling the delivery of multiple different drugs, and can be programmed to change drug regimens in response to a changing medical condition of a patient, for example in response to information from a sensor. In some embodiments, the dispenser acts as an electromechanical patch.

公开(公告)号：EP1429835A1

公开(公告)日：2004-06-23

申请号：EP02731520.9

申请日：2002-04-24

申请人： HEWLETT-PACKARD COMPANY

发明人： PICKUP, Ray, L. ,  LO, Clement, C. ,  NOONAN, William, D.

IPC分类号： A61M35/00 ,  A61M5/30 ,  A61K9/00 ,  A61M37/00 ,  A01K11/00 ,  A61M11/00 ,  A61D7/00

CPC分类号： B41J2/16535 ,  A01K11/005 ,  A01K13/003 ,  A61M5/14248 ,  A61M31/002 ,  A61M35/003 ,  A61M37/00 ,  A61M37/0084 ,  B41J2/16505 ,  B41J3/36 ,  B41J3/407

摘要： Bioactive agents are cutaneously delivered by a thermal or piezoelectric jet dispenser (30). The dispenser (30) propels precise volumes of droplets toward the skin (24), where they exert a local or topical effect, or move through the skin (24) for transdermal systemic delivery. Drugs are either delivered directly to the skin (24), or are introduced into a transdermal patch (25). The dispenser (30) can be used to resupply a transdermal patch (25) with drug instead of replacing the patch. A controller (100, 220) in the dispenser is capable of accurately controlling the delivery of multiple different drugs, and can be programmed to change drug regimens in response to a changing medical condition of a patient, for example in response to information from a sensor. In some embodiments, the dispenser acts as an electromechanical patch.