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公开(公告)号：EP2952902A4
公开(公告)日：2016-09-21
申请号：EP14745549
申请日：2014-01-27
CPC分类号： G01N35/00623 , G01N35/00871 , G01N35/1002 , G01N35/1016 , G01N2035/00633
摘要： Pressure inside the dispensing nozzle of the dispensing mechanisms 50, 60, and 70 is detected, the dispensing mechanisms dipping a dispensing nozzle in a dispensing target contained in a container 11, 21, and 31, aspirating the dispensing target, and discharging the dispensing target to a reaction container 41; one item of the determination-purpose reference data is selected from the multiple items of the determination-purpose reference data which is stored in a storage unit 93 and used in determining whether or not the dispensing mechanisms 50, 60, and 70 are abnormal, based on the detection result from the pressure sensor 54 when the dispensing mechanisms 50, 60, and 70 dispense a reference dispensing target configured to contain a known ingredient; and whether or not the dispensing mechanisms 50, 60, and 70 are abnormal is determined, based on the detection result from the pressure sensor 54 and the selected determination-purpose reference data when the dispensing mechanisms 50, 60, and 70 dispense a dispensing target used in analysis. According to this, it is possible to reliably detect abnormal dispensing in a dispensing mechanism.
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公开(公告)号：EP2876449A4
公开(公告)日：2016-03-23
申请号：EP13819196
申请日：2013-06-20
IPC分类号： G01N35/10
CPC分类号： G01N35/1016 , G01N35/00584 , G01N35/00663 , G01N35/1002 , G01N35/1009 , G01N2035/00673 , G01N2035/1018 , G01N2035/1025
摘要： Implemented is an automatic analyzer capable of performing highly reliable analysis by accurately detecting dispensation abnormality in dispensation conditions with small suction quantities. A statistical distance calculation unit 206a calculates characteristic variables regarding a sucking operation in the first dispensation and calculates a statistical distance D from reference data to the characteristic variables extracted from a memory 206b by a reference data selection unit 206f. A comparison unit 206c compares the statistical distance D with a preset threshold value stored in the memory 206b and supplies the result of the comparison to a judgment unit 206d. If the statistical distance D is less than the preset threshold value, the judgment unit 206d performs the first discharging operation. A controller judges whether a single-handed judgment based on a dispensation quantity condition of the second or subsequent dispensation is possible or not. If the single-handed judgment is impossible, reference data is selected based on a judgment quantity regarding the first dispensation. Whether the sucking operation in the second or subsequent dispensation is normal or abnormal is judged based on the selected reference data.
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公开(公告)号：EP2330426A4
公开(公告)日：2016-07-06
申请号：EP09817583
申请日：2009-07-31
IPC分类号： G01N35/10
CPC分类号： G01N35/1016 , G01N35/1004 , G01N2035/1018
摘要： A function for checking whether components of an automatic analyzer properly operate is made available. A pressure sensor is installed in a sample path. A pressure waveform obtained during a washing water discharge operation 10 is used to check the opening/closing of a solenoid valve and the other operations of a dispensing mechanism. This function can also be exercised when a pressure sensor for a conventional sample suction check process is used. Even when the solenoid valve fails to open or close, an alarm is issued to indicate such a failure. This makes it possible to prevent a sample from thinning, thereby providing enhanced data reliability.
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4.发明公开AUTOMATIC ANALYSIS DEVICE AND METHOD FOR DETERMINING MALFUNCTION THEREOF 审中-公开VERFAHREN ZUR BESTIMMUNG EINER FEHLFUNKTION DAVON汽车修理
公开(公告)号：EP2759835A4
公开(公告)日：2015-04-22
申请号：EP12833461
申请日：2012-05-17
CPC分类号： G01F23/00 , G01F23/263 , G01L7/00 , G01N35/1011 , G01N2035/009 , G01N2035/1018 , G01N2035/1025
摘要： An automatic analyzer which performs a suction operation a plurality of times on a same sample has a sample dispensing unit 9, a liquid level sensor which detects the liquid level of the sample in a sample vessel 8, an arithmetic unit 5 which computes a liquid level height h1 at the end of a first suction operation of the two consecutive suction operations from a liquid level height h0 and a sample suction volume V1 detected at the start of the first suction operation, a storage unit 7 which stores the liquid level height h1 computed by the arithmetic unit 5, and a determination unit 18 which compares a liquid level height h2 detected at the start of a second suction operation following the first suction operation with the liquid level height h1 at the end of the first suction operation. The automatic analyzer further determines the presence or absence of a failure in the first or second suction operation according to whether the difference between both liquid level heights h1 and h2 exceeds a threshold value d set in advance. Thus, it is possible to determine whether the suction operation of the sample dispensing unit has been performed properly.
摘要翻译： 在同一样品上进行多次抽吸操作的自动分析仪具有样品分注单元9，检测样品容器8中的样品的液面的液位传感器，计算液位的运算单元5 在从第一抽吸操作开始时检测到的液面高度h0和样品吸入容积V1进行两次连续抽吸操作的第一抽吸操作结束时的高度h1，存储单元7，其存储计算出的液面高度h1 以及确定单元18，其将在第一抽吸操作之后的第二抽吸操作开始时检测到的液位高度h2与在第一抽吸操作结束时的液面高度h1进行比较。 根据两个液位高度h1和h2之间的差是否超过预先设定的阈值d，自动分析器进一步确定第一或第二抽吸操作中是否存在故障。 因此，可以确定样品分注单元的抽吸操作是否已经被适当地执行。
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公开(公告)号：EP2752667A4
公开(公告)日：2015-04-22
申请号：EP12828882
申请日：2012-07-19
CPC分类号： G01N35/1002 , G01N35/1011 , G01N35/1016 , G01N2035/1018 , G01N2035/1062 , Y10T436/119163
摘要： An automatic analyzer for judging normal and abnormal of the dispensing operation for detecting abnormal condition of dispensing operation caused by various causes to execute an analysis with high reliability with no requirement of great amount of reference data is realized. A plunger 66 is moved downwardly in predetermined distance while the tip of the sample probe 15 is immersed in a sample to suck the sample into the probe. A pressure sensor 26 detects the pressure fluctuation during the suction operation, an AD converter converting the signals into digital signals to send the signals for a signal processing unit 76. The signal processing unit 76 extracts feature variables data of a suction waveform to calculate the Statistical distance D from normal group data. The Statistical distance D an a threshold value th are compared with each other, it is judged that there is an abnormality in the suction operation when the Statistical distance D is more than or equal to the threshold value th. When the Statistical distance D is smaller than the threshold value th, an operation is proceeded to a discharge operation. After the discharge operation, the values of the feature variables of the discharge waveform are extracted, and the Statistical distance D from the normal group data is calculated. When the Statistical distance d D is more than or equal to the predetermined threshold value th, it is judged that there is an abnormality.
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