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公开(公告)号：EP0619116A2
公开(公告)日：1994-10-12
申请号：EP94105021.3
申请日：1994-03-30
发明人： Shudo, Koichi , Sugioka, Tatsuo , Inazu, Mizuho , Tanaka, Hideyuki , Inoue, Tsutomu , Kitamura, Kazuyuki
CPC分类号： A61K31/655 , A61K31/19 , A61K31/192 , A61K31/195 , A61K31/196 , A61K31/336 , A61K31/35 , A61K31/352 , A61K31/44
摘要： An anti-osteopathic composition comprising as an active ingredient a compound represented by the following formula (I), (II) or (III):
which is useful for therapeutic and prophylactic treatment of osteopathia such as osteoporosis and bone fracture.摘要翻译： 一种抗骨质疏松组合物，其包含作为活性成分的由下式（I），（II）或（III）表示的化合物：
，其可用于治疗和预防性治疗骨质疏松症（例如骨质疏松症和骨折）。 -
公开(公告)号：EP0547545B1
公开(公告)日：1994-11-30
申请号：EP92121256.9
申请日：1992-12-14
发明人： Inazu, Mizuho , Satoh, Ryoichi , Inoue, Tsutomu , Kitagawa, Hiroshi , Katoh, Masakazu , Englert, Heinrich, Dr. , Carniato, Denis, Dr. , Lang, Hans-Jochen, Dr.
IPC分类号： A61K31/40 , A61K31/435
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3.发明公开Pharmaceutical composition for the inhibition of bone resorption 失效Pharmazeutische Zusammensetzung zur Inhibierung der Knochenresorption。
公开(公告)号：EP0547545A1
公开(公告)日：1993-06-23
申请号：EP92121256.9
申请日：1992-12-14
发明人： Inazu, Mizuho , Satoh, Ryoichi , Inoue, Tsutomu , Kitagawa, Hiroshi , Katoh, Masakazu , Englert, Heinrich, Dr. , Carniato, Denis, Dr. , Lang, Hans-Jochen, Dr.
IPC分类号： A61K31/40 , A61K31/435
摘要： Pharmaceutical compositions for the inhibition of bone resorption comprising a pharmaceutical carrier and a therapeutically effective amount of a benzopyran derivative represented by the general formula (I)
wherein the broken-lined bond denotes an optional double bond, R₁ denotes a hydrogen atom or a hydroxyl group, R₂ denotes a cyano group, a phenylsulfonyl group or a halogen-substituted methoxyl group, and R₃ denotes a group having the formula
or
Since they inhibit bone resorption, they are useful for the treatment and prevention of diseases associated with bone metabolism .摘要翻译： 用于抑制骨吸收的药物组合物，其包含药物载体和治疗有效量的由通式（I）表示的苯并吡喃衍生物
，其中破碎的键表示任选的双键，R 1表示氢原子或 羟基，R2表示氰基，苯基磺酰基或卤素取代的甲氧基，R3表示具有式CHEM>或CHEM的基团由于它们抑制骨吸收，因此它们可用于治疗和预防 与骨代谢相关的疾病。 -
公开(公告)号：EP0619116A3
公开(公告)日：1994-11-23
申请号：EP94105021.3
申请日：1994-03-30
发明人： Shudo, Koichi , Sugioka, Tatsuo , Inazu, Mizuho , Tanaka, Hideyuki , Inoue, Tsutomu , Kitamura, Kazuyuki
CPC分类号： A61K31/655 , A61K31/19 , A61K31/192 , A61K31/195 , A61K31/196 , A61K31/336 , A61K31/35 , A61K31/352 , A61K31/44
摘要： An anti-osteopathic composition comprising as an active ingredient a compound represented by the following formula (I), (II) or (III):
which is useful for therapeutic and prophylactic treatment of osteopathia such as osteoporosis and bone fracture.
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