公开(公告)号：EP0722459A1

公开(公告)日：1996-07-24

申请号：EP94920544.0

申请日：1994-07-11

申请人： HOLMES, Michael John ,  NYCOMED PHARMA AS ,  SMITHKLINE BEECHAM CORPORATION

发明人： AGNER, Erik ,  CUTHBERTSON, Alan ,  FISCHER, Peter ,  BHATNAGAR, Pradip ,  HUSBYN, Mette ,  UNDHEIM, Kjell

IPC分类号： A61K38 ,  A61P7 ,  A61P43 ,  C07K5 ,  C07K7

CPC分类号： C07K7/067 ,  A61K38/00

摘要： The invention relates to peptide compounds comprising two monomeric peptides having cell proliferation regulatory activity joined together by two or more divalent bridging units. Such compounds have a stimulating activity on cell division, especially for myelopoietic and bone marrow cells.

摘要翻译： 本发明涉及包含两种单体肽的肽化合物，所述单体肽具有通过两个或更多个二价桥连单位连接在一起的细胞增殖调节活性。 这些化合物对细胞分裂具有刺激活性，特别是对于骨髓生成和骨髓细胞。

公开(公告)号：EP0722459B1

公开(公告)日：1998-12-23

申请号：EP94920544.7

申请日：1994-07-11

申请人： NYCOMED IMAGING AS ,  SMITHKLINE BEECHAM CORPORATION

发明人： AGNER, Erik ,  CUTHBERTSON, Alan ,  FISCHER, Peter ,  BHATNAGAR, Pradip ,  HUSBYN, Mette ,  UNDHEIM, Kjell

IPC分类号： C07K7/06 ,  C07K5/083 ,  A61K38/08

CPC分类号： C07K7/067 ,  A61K38/00

摘要： The invention relates to peptide compounds comprising two monomeric peptides having cell proliferation regulatory activity joined together by two or more divalent bridging units. Such compounds have a stimulating activity on cell division, especially for myelopoietic and bone marrow cells.