摘要:
The present invention is related to novel preparative methods to a novel class of polymer network materials with a highly branched poly(glycidyl ether) (PGE) structure. Said polymer networks are prepared by a simple procedure involving cationic ring-opening polymerisation and the method is applicable to a wide range of glycidyl ether containing monomers. The method comprises either the step of homopolymerising at least one multi-topic glycidyl ether comprising at least three glycidyl ether groups or the step of copolymerising (A) at least one multi-topic glycidyl ether comprising at least three glycidyl ether groups with (B) at least one glycidyl ether component comprising at least one glycidyl ether group by ring opening polymerisation.
摘要:
The present invention relates to an article consisting of or comprising a bidirectional shape-memory polymer (bSMP), the bSMP comprising: first phase-segregated domains (AD) having a first transition temperature (Tt,AD) corresponding to a crystallization transition or glass transition of the first domains (AD), second phase-segregated domains (SD) having a second transition temperature (Tt,AD) corresponding to a crystallization transition or glass transition of the second domains (SD), the second transition temperature (Tt,SD) being higher than the first transition temperature (Tt,AD), and covalent or physical bonds cross-linking the polymer chains of the bSMP, and in this way interconnecting the first and second domains (AD, SD), wherein the second phase-separated domains (SD) form a skeleton which is at least partially embedded in the first phase-segregated domains (AD), and wherein polymer chain segments of the bSMP forming the first domains (AD) are substantially orientated in a common direction, such that the bSMP is able to undergo a reversible shape-shift between a first shape (A) at a first temperature (Thigh) and a second shape (B) at a second temperature (Tlow) upon variation of temperature between the first and second temperature (Thigh, Tlow) driven by the crystallization and melting or vitrification and melting of the first phase-separated domains (AD) and without application of an external stress, with Tlow
摘要:
The invention relates to a method for testing various selected materials and/or surface structures for culturing cells and/or microorganisms, comprising the steps of: i) providing a plurality of various selected materials and/or surface structures to be tested in the form of cup-shaped inserts, wherein the cup-shaped inserts are sized such that a cup-shaped insert can be inserted into a recess of a multi-well plate suitable for cell culturing in a substantially precisely-fit manner, wherein each cup-shaped insert has walls, a floor and an opening on the side facing away from the floor, wherein the walls and floor of the cup-shaped inserts are designed to be fluid-sealed and wherein each cup-shaped insert has one selected material and/or selected surface structure at least on the inner face of the floor; ii) inserting the cup-shaped inserts in recesses of multi-well plates of corresponding sizing such that the exterior side of the cup floor points in the direction of the interior side of the floor of a recess of the multi-well plate; and iii) culturing of cells in the lumen of the cup-shaped inserts. The invention further relatets to a kit for performing said method.
摘要:
The invention relates to a method for producing a programmed shape-memory polymer which assumes a first temporary shape and has at least two further stored, thermally retrievable shapes, to be specific at least a second temporary shape and a permanent shape, with the steps of (a) providing a shape-memory polymer, which comprises at least two switching segments (A, B), which are capable by phase segregation of respectively forming a switching phase with in each case a transition temperature (Ttrans,A, Ttrans,B), (b) deforming the shape-memory polymer into a shape corresponding to the first temporary shape at a temperature above the upper transition temperature (Ttrans,A), and (c) cooling to a temperature below the lower transition temperature (Ttrans,B), thereby fixing the first temporary shape. The method according to the invention provides a one-step programming method for a three-shape plastic.
摘要:
The invention provides a surface-functionalised polymeric object (10), comprising: a bulk material (11) comprising a copolymer containing constitution units derived from a first comonomer and constitution units derived from a second comonomer, the first comonomer being selected from L-lactide and D-lactide and forming sequences of oligo(L-lactide) or oligo(D-lactide) in the copolymer; and a surface layer (12) disposed on a surface of the bulk material (11), the surface layer (12) comprising a functionalising species and at least one chain of poly(D-lactide) or of poly(L-lactide) covalently bound to the functionalising species, and at least one chain being different from the oligo(L-lactide) sequences or oligo(D-lactide) sequences contained in the copolymer; wherein the surface layer (12) is attached to the bulk material (11) via stereocomplexes formed between the poly(D-lactide) chain(s) of the functionalising species and the oligo(L-lactide) sequences contained in the copolymer or via stereocomplexes formed between the poly(L-lactide) chain(s) of the functionalising species and the oligo(D-lactide) sequences contained in the copolymer, respectively. The surface-functionalised polymeric object can be produced in a one-step procedure by coaxial electrospinning.