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公开(公告)号：EP2615101B1
公开(公告)日：2018-10-17
申请号：EP11823062.2
申请日：2011-09-02
申请人： High & New Technology Research Center, Henan Academy of Sciences , Zhengzhou Granlen Pharmatech Ltd. , Zhengzhou University
发明人： CHANG, Junbiao , AN, Haoyun , YU, Xuejun , GUO, Xiaohe
IPC分类号： C07H19/06 , C07H1/00 , A61K31/7068 , A61P35/00 , A61P35/02 , A61P31/12 , A61P31/20 , A61P31/14 , A61P31/18 , A61P31/22
摘要： The present invention relates to the field of pharmacochemistry. Disclosed are fluorinated and azido-substituted pyrimidine nucleoside derivatives, and preparation methods and uses thereof. The structural formula is as shown (I). These compounds can be used for preparing medicaments for treating diseases such as tumors and viral infections, and can be used separately or in combination with other medicaments. The compounds also have effective activity against diseases such as tumors and viral infections, while having few side effects, and thus have potential application value.
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2.发明公开NUCLEOSIDE DERIVATIVES, SYNTHESIS METHODS AND USES THEREOF FOR PREPARING ANTI-TUMOR AND ANTI-VIRUS MEDICAMENTS 审中-公开核苷，使用合成方法和抗肿瘤和抗病毒产品的制备
公开(公告)号：EP2615101A1
公开(公告)日：2013-07-17
申请号：EP11823062.2
申请日：2011-09-02
申请人： High & New Technology Research Center, Henan Academy of Sciences , Zhengzhou Granlen Pharmatech Ltd. , Zhengzhou University
发明人： CHANG, Junbiao , AN, Haoyun , YU, Xuejun , GUO, Xiaohe
IPC分类号： C07H19/06 , C07H1/00 , A61K31/7068 , A61P35/00 , A61P35/02 , A61P31/12 , A61P31/20 , A61P31/14 , A61P31/18 , A61P31/22
摘要： The present invention relates to the field of pharmacochemistry. Disclosed are fluorinated and azido-substituted pyrimidine nucleoside derivatives, and preparation methods and uses thereof. The structural formula is as shown (I). These compounds can be used for preparing medicaments for treating diseases such as tumors and viral infections, and can be used separately or in combination with other medicaments. The compounds also have effective activity against diseases such as tumors and viral infections, while having few side effects, and thus have potential application value.
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3.发明公开
公开(公告)号：EP3363803A1
公开(公告)日：2018-08-22
申请号：EP16854873.3
申请日：2016-09-22
发明人： LI, Runtao , AN, Haoyun , HAN, Liqiang , GE, Zemei , CUI, Jingrong , CHENG, Tieming
IPC分类号： C07F5/02 , C07C229/02 , A61K31/69 , A61P35/00
摘要： The present invention provides a urea peptidomimetic boronic compound and pharmaceutical compositions thereof, their preparative methods and uses. The compounds are represented by the following formula ( I ).
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公开(公告)号：EP3363803B1
公开(公告)日：2020-08-12
申请号：EP16854873.3
申请日：2016-09-22
发明人： LI, Runtao , AN, Haoyun , HAN, Liqiang , GE, Zemei , CUI, Jingrong , CHENG, Tieming
IPC分类号： C07F5/02 , C07C229/02 , A61K31/69 , A61P35/00
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