专利检索 ap:("Histide AG") AND inv:"GOCHEVA, Veronika" 第 1 页

1.

发明公开
PHARMACEUTICAL ASSOCIATION OF GROWTH FACTOR RECEPTOR AGONIST AND ADHESION PROTEIN INHIBITOR FOR CONVERTING A NEOPLASTIC CELL INTO A NON-NEOPLASTIC CELL AND USES THEREOF 审中-公开

公开(公告)号：EP3906932A2

公开(公告)日：2021-11-10

申请号：EP20214632.0

申请日：2016-09-15

申请人： Histide AG

发明人： ZOUANI, OMAR , GOCHEVA, Veronika

IPC分类号： A61K38/05 , A61K38/07 , A61K38/08 , A61K38/10 , A61K38/12 , A61K38/16 , A61K39/395 , A61K45/06 , A61K31/70 , C07K16/28 , A61P35/00 , A61K38/18 , A61K31/7105 , A61P43/00 , C12N15/113

摘要： A pharmaceutical association comprising at least one growth factor receptor-binding compound, which activates at least one growth factor receptor of a neoplastic cell, and at least one adhesion protein inhibitor which inhibits at least one transmembrane cell adhesion protein of said neoplastic cell.

2.

发明公开
PHARMACEUTICAL ASSOCIATION OF GROWTH FACTOR RECEPTOR AGONIST AND ADHESION PROTEIN INHIBITOR FOR CONVERTING A NEOPLASTIC CELL INTO A NON-NEOPLASTIC CELL AND USES THEREOF 审中-公开

公开(公告)号：EP3906932A3

公开(公告)日：2021-12-01

申请号：EP20214632.0

申请日：2016-09-15

申请人： Histide AG

发明人： ZOUANI, OMAR , GOCHEVA, Veronika

IPC分类号： A61K38/05 , A61K38/07 , A61K38/08 , A61K38/10 , A61K38/12 , A61K38/16 , A61K39/395 , A61K45/06 , A61K31/70 , C07K16/28 , A61P35/00 , A61K38/18 , A61K31/7105 , A61P43/00 , C12N15/113

摘要： A pharmaceutical association comprising at least one growth factor receptor-binding compound, which activates at least one growth factor receptor of a neoplastic cell, and at least one adhesion protein inhibitor which inhibits at least one transmembrane cell adhesion protein of said neoplastic cell.

3.

发明公开
PHARMACEUTICAL ASSOCIATION COMPRISING A GROWTH FACTOR RECEPTOR AGONIST CONJUGATED TO A BIOACTIVE CARRIERFOR CONVERTING A NEOPLASTIC CELL INTO A NON-NEOPLASTIC CELL AND USES THEREOF 审中-公开

公开(公告)号：EP3349777A2

公开(公告)日：2018-07-25

申请号：EP16770462.6

申请日：2016-09-15

申请人： Histide AG

发明人： ZOUANI, Omar F. , GOCHEVA, Veronika

IPC分类号： A61K38/05 , A61L27/12 , A61L27/34 , A61K38/07 , A61K38/08 , A61K38/10 , A61K38/12 , A61L27/54 , A61K38/18 , A61K9/16 , G06F19/16

CPC分类号： A61K38/18 , A61K38/05 , A61K38/07 , A61K38/08 , A61K38/10 , A61K38/12 , G06F19/16

摘要： The present disclosure provides a pharmaceutical association for use in the treatment, prevention and/or diagnostic of a neoplastic disease, said association comprising at least one growth factor receptor-binding compound, which activates at least one growth factor receptor of a neoplastic cell, and at least one bioactive carrier forming at least one covalent or non-covalent interaction with said at least one growth factor receptor-binding compound, and wherein said association reduces or suppresses, in the neoplastic cell, the gene expression of at least one cyclin D and/or reduces or suppresses the formation of at least one complex formed between said at least one cyclin D and at least one of cyclin dependent-kinase 4 or 6.

4.

发明公开
PHARMACEUTICAL ASSOCIATION OF GROWTH FACTOR RECEPTOR AGONIST AND ADHESION PROTEIN INHIBITOR FOR CONVERTING A NEOPLASTIC CELL INTO A NON-NEOPLASTIC CELL AND USES THEREOF 审中-公开

公开(公告)号：EP3998076A1

公开(公告)日：2022-05-18

申请号：EP21187057.1

申请日：2016-09-15

申请人： Histide AG

发明人： ZOUANI, OMAR , GOCHEVA, Veronika

IPC分类号： A61K38/05 , A61K38/07 , A61K38/08 , A61K38/10 , A61K38/18 , A61K45/06 , A61P35/00 , A61P43/00 , C07K16/28 , C12N15/113 , A61K38/12 , A61K31/7105 , A61K31/713 , A61K39/395

摘要： The present disclosure provides a pharmaceutical association comprising at least one growth factor receptor-binding compound, which activates at least one growth factor receptor of a neoplastic cell, and at least one adhesion protein inhibitor which inhibits at least one transmembrane cell adhesion protein of said neoplastic cell.

5.

发明公开
PHARMACEUTICAL ASSOCIATION OF GROWTH FACTOR RECEPTOR AGONIST AND ADHESION PROTEIN INHIBITOR FOR CONVERTING A NEOPLASTIC CELL INTO A NON-NEOPLASTIC CELL AND USES THEREOF 审中-公开

公开(公告)号：EP3949975A1

公开(公告)日：2022-02-09

申请号：EP21187038.1

申请日：2016-09-15

申请人： Histide AG

发明人： ZOUANI, OMAR , GOCHEVA, Veronika

IPC分类号： A61K38/05 , A61K38/07 , A61K38/08 , A61K38/10 , A61K38/12 , A61K38/16 , A61K39/395 , A61K45/06 , A61K31/70 , C07K16/28 , A61P35/00 , A61K38/18 , A61K31/713 , A61P43/00

摘要： The present disclosure provides a pharmaceutical association comprising at least one growth factor receptor-binding compound, which activates at least one growth factor receptor of a neoplastic cell, and at least one adhesion protein inhibitor which inhibits at least one transmembrane cell adhesion protein of said neoplastic cell.

6.

发明公开
PHARMACEUTICAL ASSOCIATION COMPRISING A GROWTH FACTOR RECEPTOR AGONIST CONJUGATED TO A BIOACTIVE CARRIER FOR CONVERTING A NEOPLASTIC CELL INTO A NON-NEOPLASTIC CELL AND USES THEREOF 审中-公开

公开(公告)号：EP3349782A2

公开(公告)日：2018-07-25

申请号：EP16770237.2

申请日：2016-09-15

申请人： Histide AG

发明人： ZOUANI, Omar F. , GOCHEVA, Veronika

IPC分类号： A61K38/18 , A61L27/12 , A61L27/34 , A61K38/05 , A61K38/07 , A61K38/08 , A61K38/10 , A61K38/12 , A61L27/54 , A61K9/16 , G06F19/16 , A61P35/00

CPC分类号： A61K38/18 , A61K38/05 , A61K38/07 , A61K38/08 , A61K38/10 , A61K38/12 , A61K38/1875 , A61K47/50 , A61L27/12 , A61L27/22 , A61L27/24 , A61L27/34 , A61L27/40 , A61L27/54 , A61L2300/416 , A61L2400/06 , A61L2430/02

摘要： The present disclosure provides a pharmaceutical association for use in the treatment, prevention and/or diagnostic of a neoplastic disease, said association comprising at least one growth factor receptor-binding compound, which activates at least one growth factor receptor of a neoplastic cell, and at least one bioactive carrier forming at least one covalent or non-covalent interaction with said at least one growth factor receptor-binding compound, and wherein said association reduces or suppresses, in the neoplastic cell, the gene expression of at least one cyclin D and/or reduces or suppresses the formation of at least one complex formed between said at least one cyclin D and at least one of cyclin dependent-kinase 4 or 6.

7.

发明公开
PHARMACEUTICAL ASSOCIATION OF GROWTH FACTOR RECEPTOR AGONIST AND ADHESION PROTEIN INHIBITOR FOR CONVERTING A NEOPLASTIC CELL INTO A NON-NEOPLASTIC CELL AND USES THEREOF 审中-公开

公开(公告)号：EP3349778A2

公开(公告)日：2018-07-25

申请号：EP16770464.2

申请日：2016-09-15

申请人： Histide AG

发明人： ZOUANI, Omar F. , GOCHEVA, Veronika

IPC分类号： A61K38/05 , A61K38/07 , A61K38/08 , A61K38/10 , A61K38/12 , A61K38/16 , A61K39/395 , A61K45/06 , A61K31/70 , C07K16/28 , A61P35/00 , A61K38/18 , G06F19/16

CPC分类号： A61K38/18 , A61K31/713 , A61K38/05 , A61K38/07 , A61K38/08 , A61K38/10 , A61K38/12 , A61K39/39558 , A61K45/06 , C07K16/2839 , C07K16/2842 , A61K2300/00

摘要： The present disclosure provides a pharmaceutical association comprising at least one growth factor receptor-binding compound, which activates at least one growth factor receptor of a neoplastic cell, and at least one adhesion protein inhibitor which inhibits at least one transmembrane cell adhesion protein of said neoplastic cell.

8.

发明公开
PHARMACEUTICAL ASSOCIATION OF GROWTH FACTOR RECEPTOR AGONIST AND ADHESION PROTEIN INHIBITOR FOR CONVERTING A NEOPLASTIC CELL INTO A NON-NEOPLASTIC CELL AND USES THEREOF 审中-公开

公开(公告)号：EP3349776A2

公开(公告)日：2018-07-25

申请号：EP16766294.9

申请日：2016-09-15

申请人： Histide AG

发明人： ZOUANI, Omar F. , GOCHEVA, Veronika

IPC分类号： A61K38/05 , A61K38/07 , A61K38/08 , A61K38/10 , A61K38/12 , A61K38/16 , A61K39/395 , A61K45/06 , A61K31/70 , C07K16/28 , A61P35/00 , A61K38/18 , G06F19/16

CPC分类号： A61K38/18 , A61K31/7105 , A61K38/05 , A61K38/07 , A61K38/08 , A61K38/10 , A61K38/12 , A61K45/06 , C07K16/2839 , C07K2317/70 , C07K2317/76 , C12N15/113 , C12N2310/14 , C12N2310/531

摘要： A pharmaceutical association comprising at least one growth factor receptor-binding compound, which activates at least one growth factor receptor of a neoplastic cell, and at least one adhesion protein inhibitor which inhibits at least one transmembrane cell adhesion protein of said neoplastic cell.

搜索结果

国家/区域

专利有效性

申请日

公布(公告)日

申请人

申请人所在国/区域

发明人

IPC

IPC部

IPC大类

IPC小类

IPC大组

IPC小组

外观分类