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公开(公告)号：EP2496697A2
公开(公告)日：2012-09-12
申请号：EP10829090.9
申请日：2010-11-04
发明人： LOOGER, Loren, Lee , TIAN, Lin
IPC分类号： C12N15/12 , C12Q1/68 , C07K14/705 , G01N33/68
CPC分类号： C07K14/4728 , C07K2319/60 , G01N33/5035
摘要： Provided herein are nucleic acid sequences and polypeptides encoding a genetically encoded calcium indicator (GECI). Also provided are vectors and cells comprising the nucleic acid sequences and/or polypeptides. Kits comprising the nucleic acid sequences, polypeptides, vectors, cells and combinations thereof are also provided. Also provided herein are methods of screening for G-protein coupled receptor (GPCR) agonists and antagonists and methods of monitoring neural activity using the GECIs.
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2.发明授权GENETICALLY ENCODED CALCIUM INDICATORS AND METHODS OF USE 有权GENETISCH KODIERTE CALCIUMINDIKATOREN UND VERWENDUNGSVERFAHRENDAFÜR
公开(公告)号：EP2496697B1
公开(公告)日：2017-04-12
申请号：EP10829090.9
申请日：2010-11-04
发明人： LOOGER, Loren, Lee , TIAN, Lin
IPC分类号： C12N15/12 , C12Q1/68 , C07K14/705 , G01N33/68
CPC分类号： C07K14/4728 , C07K2319/60 , G01N33/5035
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