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公开(公告)号：EP2222710B8
公开(公告)日：2016-10-12
申请号：EP08864495.0
申请日：2008-12-23
IPC分类号： C07K19/00 , A61K39/00 , A61K39/155 , A61K39/295 , A61K9/107 , A61K9/127 , A61P31/14 , A61P37/04 , C07K14/135 , C12N15/45 , C12N15/62 , C07K14/005
CPC分类号： C07K14/005 , A61K39/12 , A61K39/155 , A61K2039/55505 , A61K2039/55572 , A61K2039/55577 , C07K16/1027 , C07K2317/21 , C07K2317/76 , C07K2319/73 , C12N2760/18522 , C12N2760/18534 , Y02A50/466
摘要： This disclosure provides recombinant respiratory syncytial virus (RSV) antigens and methods for making and using them, including immunogenic compositions (e.g., vaccines) for the treatment and/or prevention of RSV infection.
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公开(公告)号：EP3109258B1
公开(公告)日：2019-01-23
申请号：EP16180926.4
申请日：2008-12-23
IPC分类号： C07K19/00 , A61K39/00 , A61K39/155 , A61K39/295 , A61K9/107 , A61K9/127 , A61P31/14 , A61P37/04 , C07K14/135 , C12N15/45 , C12N15/62 , C07K14/005 , A61K39/12
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公开(公告)号：EP2445526A1
公开(公告)日：2012-05-02
申请号：EP10724879.1
申请日：2010-06-24
发明人： BAUDOUX, Guy Jean Marie Fernand Pierre , BLAIS, Normand , CYR, Sonya L , RHEAULT, Patrick , RUELLE, Jean Louis
IPC分类号： A61K39/155 , C07K14/135
CPC分类号： A61K39/155 , A61K39/12 , A61K2039/55505 , A61K2039/55566 , A61K2039/55572 , A61K2039/55577 , C07K14/005 , C07K2319/70 , C07K2319/73 , C12N2760/18522 , C12N2760/18534
摘要： This disclosure provides recombinant respiratory syncytial virus (RSV) antigens and methods for making and using them, including immunogenic compositions (e.g., vaccines) for the treatment and/or prevention of RSV infection.
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公开(公告)号：EP4219566A3
公开(公告)日：2023-09-06
申请号：EP23150323.6
申请日：2008-12-23
IPC分类号： C07K19/00 , A61K39/00 , A61K39/155 , A61K39/295 , A61K9/107 , A61K9/127 , A61P31/14 , A61P37/04 , C07K14/135 , C12N15/45 , C12N15/62 , C07K14/005 , A61K39/12
摘要： This disclosure provides recombinant respiratory syncytial virus (RSV) antigens and methods for making and using them, including immunogenic compositions (e.g. vaccines) for the treatment and/or prevention of RSV infection.
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公开(公告)号：EP3508505A1
公开(公告)日：2019-07-10
申请号：EP19152924.7
申请日：2008-12-23
IPC分类号： C07K19/00 , A61K39/00 , A61K39/155 , A61K39/295 , A61K9/107 , A61K9/127 , A61P31/14 , A61P37/04 , C07K14/135 , C12N15/45 , C12N15/62 , C07K14/005 , A61K39/12
摘要： This disclosure provides recombinant respiratory syncytial virus (RSV) antigens and methods for making and using them, including immunogenic compositions (e.g., vaccines) for the treatment and/or prevention of RSV infection.
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公开(公告)号：EP2222710B1
公开(公告)日：2016-07-27
申请号：EP08864495.0
申请日：2008-12-23
IPC分类号： C07K19/00 , A61K39/00 , A61K39/155 , A61K39/295 , A61K9/107 , A61K9/127 , A61P31/14 , A61P37/04 , C07K14/135 , C12N15/45 , C12N15/62 , C07K14/005
CPC分类号： C07K14/005 , A61K39/12 , A61K39/155 , A61K2039/55505 , A61K2039/55572 , A61K2039/55577 , C07K16/1027 , C07K2317/21 , C07K2317/76 , C07K2319/73 , C12N2760/18522 , C12N2760/18534 , Y02A50/466
摘要： This disclosure provides recombinant respiratory syncytial virus (RSV) antigens and methods for making and using them, including immunogenic compositions (e.g., vaccines) for the treatment and/or prevention of RSV infection.
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公开(公告)号：EP2445526B1
公开(公告)日：2016-05-11
申请号：EP10724879.1
申请日：2010-06-24
发明人： BAUDOUX, Guy Jean Marie Fernand Pierre , BLAIS, Normand , CYR, Sonya L , RHEAULT, Patrick , RUELLE, Jean Louis
IPC分类号： A61K39/155 , C07K14/135
CPC分类号： A61K39/155 , A61K39/12 , A61K2039/55505 , A61K2039/55566 , A61K2039/55572 , A61K2039/55577 , C07K14/005 , C07K2319/70 , C07K2319/73 , C12N2760/18522 , C12N2760/18534
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公开(公告)号：EP2445527A2
公开(公告)日：2012-05-02
申请号：EP10728203.0
申请日：2010-06-24
IPC分类号： A61K39/155
CPC分类号： A61K39/155 , A61K39/12 , A61K39/17 , A61K2039/555 , A61K2039/55566 , A61K2039/70 , C07K14/005 , C07K2319/00 , C07K2319/73 , C12N2760/18322 , C12N2760/18334 , C12N2760/18522 , C12N2760/18534 , C12N2760/18622 , C12N2760/18634
摘要： The present disclosure provides immunogenic compositions that include at least two paramyxovirus F protein antigens selected from human metapnuemovirus (hMPV), paarainfluenza virus (PIV) and respiratory syncytial virus (RSV). The antigens of the disclosed compositions are recombinant F protein polypeptides, which have been modified to stabilize the trimeric prefusion conformation. Nucleic acids encoding the antigens, as well as methods for their production and use are also provided.
摘要翻译： 本公开内容提供了免疫原性组合物，其包含至少两种选自人类偏瘫病毒（hMPV），副流感病毒（PIV）和呼吸道合胞病毒（RSV）的副粘病毒F蛋白抗原。 公开的组合物的抗原是重组F蛋白多肽，其已被修饰以稳定三聚体融合前构象。 还提供了编码抗原的核酸以及它们的生产和使用方法。
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公开(公告)号：EP2222710A1
公开(公告)日：2010-09-01
申请号：EP08864495.0
申请日：2008-12-23
IPC分类号： C07K19/00 , A61K39/00 , A61K39/155 , A61K39/295 , A61K9/107 , A61K9/127 , A61P31/14 , A61P37/04 , C07K14/135 , C12N15/45 , C12N15/62
CPC分类号： C07K14/005 , A61K39/12 , A61K39/155 , A61K2039/55505 , A61K2039/55572 , A61K2039/55577 , C07K16/1027 , C07K2317/21 , C07K2317/76 , C07K2319/73 , C12N2760/18522 , C12N2760/18534 , Y02A50/466
摘要： This disclosure provides recombinant respiratory syncytial virus (RSV) antigens and methods for making and using them, including immunogenic compositions (e.g., vaccines) for the treatment and/or prevention of RSV infection.
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公开(公告)号：EP4219566A2
公开(公告)日：2023-08-02
申请号：EP23150323.6
申请日：2008-12-23
IPC分类号： C07K19/00 , A61K39/00 , A61K39/155 , A61K39/295 , A61K9/107 , A61K9/127 , A61P31/14 , A61P37/04 , C07K14/135 , C12N15/45 , C12N15/62 , C07K14/005 , A61K39/12
摘要： This disclosure provides recombinant respiratory syncytial virus (RSV) antigens and methods for making and using them, including immunogenic compositions (e.g. vaccines) for the treatment and/or prevention of RSV infection.
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