专利检索 ap:("IND TECH RES INST") AND inv:"LEE JENQ-CHANG" 第 1 页

1.

发明公开
BIOMARKERS FOR RECURRENCE PREDICTION OF COLORECTAL CANCER 审中-公开
标题翻译：生物标记预测复发直肠癌

公开(公告)号：EP2619587A4

公开(公告)日：2013-11-13

申请号：EP12733946

申请日：2012-01-11

申请人： IND TECH RES INST

发明人： WANG TING-HUEI , LI YEN-PENG , KUO PEI-FEN , CHEN SHIH-YA , LIN CHIA-JU , LEE JENQ-CHANG , LEE ANGELINA HUAI-LO

IPC分类号： C12Q1/68 , G06F19/18

CPC分类号： C12Q1/6886 , C12Q2600/118 , C12Q2600/158 , C12Q2600/178 , G06F19/18

摘要： Methods for determining the likelihood of colorectal cancer (CRC) recurrence in a subject that involve measuring the expression level of two or more micro ribonucleic acids (miRNAs) in a biological sample comprising CRC tumor cells from said subject and using the normalized, measured expression levels to determine the likelihood of colorectal cancer recurrence for said subject. In the methods, the normalized expression levels of specific miRNAs are weighted by their contribution to CRC recurrence to calculate the likelihood of CRC recurrence. Kits for measuring the expression level of specific miRNAs that can be used in determining the likelihood of CRC recurrence are also provided.