公开(公告)号：EP2831565A4

公开(公告)日：2015-04-15

申请号：EP13768319

申请日：2013-03-26

Applicant: INNOVATIVE SCIENCE TOOLS INC

Inventor： MICHEELS RONALD H ,  LEE DON J

IPC: G01N21/3563 ,  G01J3/02 ,  G01N21/3577 ,  G01N21/359 ,  G01N21/85 ,  G01N21/95 ,  G02B6/42

CPC classification number: G01N21/255 ,  G01J3/021 ,  G01J3/0218 ,  G01J3/18 ,  G01N21/3563 ,  G01N21/3577 ,  G01N21/359 ,  G01N21/8507 ,  G01N21/9508 ,  G01N2021/475 ,  G01N2021/4759 ,  G01N2201/0627 ,  G01N2201/0631 ,  G02B6/4298

Abstract: A device and method for identifying solid and powdered materials use near-infrared reflection spectroscopy combined with multivariate calibration methods for analysis of the spectral data. Near-infrared reflection spectroscopy is employed within either the 700-1100 nm or the 900-1700 nm wavelength range to identify solid or powdered materials and determine whether they match specific known materials. Uses include identifying solid and powdered materials with a fast measurement cycle time of about 2 to 15 seconds and with a method that requires no sample preparation, as well as quantitative analysis to determine the concentration of one or more chemical components in a solid or powdered sample that consists of a mixture of components. A primary application involving identification analysis verification of the identify and purity of powdered materials used for fabricating drug tablets and capsules for quality control purposes.

Abstract translation: 用于识别固体和粉末材料的装置和方法使用近红外反射光谱结合多变量校准方法来分析光谱数据。 在700-1100nm或900-1700nm波长范围内采用近红外反射光谱法来鉴定固体或粉末材料，并确定它们是否与特定的已知材料相匹配。 用途包括以大约2至15秒的快速测量周期时间确定固体和粉末材料，并采用不需要样品制备的方法，以及定量分析来确定固体或粉末样品中一种或多种化学成分的浓度 它由组分的混合物组成。 涉及用于制造药物片剂和胶囊用于质量控制目的的粉末材料的鉴定和纯度的识别分析验证的主要应用。

公开(公告)号：EP2831566A4

公开(公告)日：2015-04-22

申请号：EP13768596

申请日：2013-03-26

Applicant: INNOVATIVE SCIENCE TOOLS INC

Inventor： MICHEELS RONALD H ,  LEE DON J

IPC: G01N21/3563 ,  G01J3/10 ,  G01N21/3577 ,  G01N21/359 ,  G01N21/95

CPC classification number: G01N21/359 ,  G01J3/0205 ,  G01J3/0216 ,  G01J3/0218 ,  G01J3/10 ,  G01J3/42 ,  G01N21/3563 ,  G01N21/3577 ,  G01N21/9508 ,  G01N2201/06153 ,  G01N2201/0627 ,  G01N2201/0631

Abstract: A device and method for identifying solid and liquid materials use near-infrared transmission spectroscopy combined with multivariate calibration methods for analysis of the spectral data. Near-infrared transmission spectroscopy is employed within either the 700-1100 nm or the 900-1700 nm wavelength range to identify solid or liquid materials and determine whether they match specific known materials. Uses include identifying solid (including powdered) and liquid materials with a fast measurement cycle time of about 2 to 15 seconds and with a method that requires no sample preparation, as well as quantitative analysis to determine the concentration of one or more chemical components in a solid or liquid sample that consists of a mixture of components. A primary application of such analysis includes detection of counterfeit drug tablets, capsules and liquid medications.