摘要:
A portable device (100) for detecting explosive substances comprises a device (200) for generating and measuring the emission of an indicator (120). The indicator has a carrier (122) and multiple indicator substances (125-1, 125-2) which can be applied with analytes (190), and which are applied to the carrier (122) as a thin layer and can be positioned in an indicator surface (130) by means of a holding device (180). The indicator substances (125-1, 125-2) are arranged in different regions of the carrier (122) such that the indicator substances in the indicator surface (130) represent a pattern of indicator substances according to the location. The device (200) comprises multiple radiation sources (210-1, 210-2) for the output of quasi-monochromatic excitation radiation. The radiation sources are arranged at different locations in a radiation surface (240) such that the radiation surface represents a pattern of radiation sources (210-1, 210-2) according to the location. Furthermore, the device has an excitation beam path with at least one first display system for displaying excitation radiation into the indicator surface (130) such that emission of the indicator substances can be generated at the locations where the the excitation radiation is displayed on the indicator surface Furthermore, an emission beam path having at least one second display system for displaying the indicator surface in a receiving surface (245) is provided such that a pattern of emissions can be generated in the receiving surface according to the location. The device (200) comprises multiple receivers (270-1, 270-2) for receiving emissions from the receiving surface and for converting the received emissions into electrical signals.
摘要:
Die Erfindung betrifft eine Vorrichtung (1) zur Ermittlung der Wirkung von Wirkstoffen an Nematoden und anderen Organismen in wässrigen Tests, umfassend eine Halterung (40) zur Aufnahme einer Zellkulturplatte (50) mit Kavitäten (57), in die sich die Nematoden mit den Wirkstoffen füllen lassen, wobei die Zellkulturplatte (50) eine Unterseite (51), eine Oberseite (62) sowie mehrere Seitenflächen aufweist, die sich zwischen Unterseite (51) und Oberseite (52) erstrecken, eine Kamera (20), die dazu dient, Bilder von vorzugsweise der Unterseite (51) der Zellkulturplatte (50) aufzunehmen, und eine Beleuchtungseinrichtung (30) zur Ausleuchtung der Zellkulturplatte (50), wobei die Beleuchtungseinrichtung (30) mehrere Lichtquellen umfasst. Erfindungsgemäß ist vorgesehen, dass in Einsatzlage der Zellkulturplatte (50) das Licht einer ersten Lichtquelle (31) durch eine erste Seitenfläche (53), das Licht einer zweiten Lichtquelle (32) durch eine zweite Seitenfläche (54), das Licht einer dritten Lichtquelle (33) durch eine dritte Seitenfläche (55), und das Licht einer vierten Lichtquelle (34) durch eine vierte Seitenfläche (56) von außen in die Zellkulturplatte (50) tritt. Zudem betrifft die Erfindung ein Verfahren zur Justierung der einzelnen Lichtquellen.
摘要:
Reflektierende bzw. geprägte Bereiche sollen für eine optische Inspektion über einen möglichst großen Winkelbereich möglichst einheitlich beleuchtet werden.
摘要:
Systems and methods are used to detect spectral and spatial information in a continuous flow PCR system. An incident beam of electromagnetic radiation is emitted using a laser. The incident beam is received from the laser and incident beam is transformed into an incident line of electromagnetic radiation using a line generator. The incident line is received from the line generator using a tube array that includes one or more transparent tubes in fluid communication with one or more micro-channels. Reflected electromagnetic radiation is received from the tube array and the reflected electromagnetic radiation is focused using an imaging lens. The focused reflected electromagnetic radiation is received from the imaging lens and a spectral intensity is detected from the focused reflected electromagnetic radiation using a spectrograph. The focused reflected electromagnetic radiation is received from the imaging lens and a location of the spectral intensity is detected using an imager.
摘要:
A ring light illuminator with annularly arranged light sources is disclosed. To each light source there corresponds a light collector, a homogenizing means for light from the light source, and an anamorphic system for imaging an output of the homogenizing means into an area to be illuminated. The anamorphic system compensates deformations of a cross-sectional area of a light beam in a surface to be illuminated due to an oblique angle of incidence of the light beam onto the surface. The homogenizing means in embodiments is a rod, into which light from the light collector is directed. The end of the rod opposite the light collector is imaged by the anamorphic system into the area to be illuminated on the surface. Also disclosed is a method for illumination.
摘要:
A ring light illuminator with annularly arranged light sources is disclosed. To each light source there corresponds a beam shaper comprising a light collector, a homogenizing means for light from the light source, and an imaging means for imaging an output of the homogenizing means into an area to be illuminated. The homogenizing means in embodiments is a rod, into which light from the light collector is directed. The end of the rod opposite the light collector is imaged by the imaging means into the area to be illuminated.
摘要:
The present invention relates to a real-time PCR monitoring apparatus for real-time monitoring production of reaction product produced during the reaction while performing nucleic acid amplification such as PCR for various kinds of trace samples. Specifically, the present invention relates to an apparatus for real-time monitoring biochemical reaction for efficiently dividing interference between an excitation light and a fluorescence, which includes a polarizer, a polarizing beam splitter, a polarization converter and so on.
摘要:
An apparatus and method are provided for creating an image of a microarray. The apparatus includes at least one light source configured to direct light toward the microarray. The apparatus includes an excitation filter configured to filter the light into a first frequency band towards dichromatic mirror. The dichromatic mirror reflects light onto the microarray causing the microarray to emit electromagnetic energy. The apparatus includes emission filter configured to filter the electromagnetic energy within a second frequency band. The apparatus further includes an imaging unit having a charged coupled device (CCD), the CC having an Imaging surface masked by a pinhole blind such that when the pinhole blind receives electromagnetic energy from the emission filter, an image is created of the entire microarray.
摘要:
A method for analyzing properties of a sampIe by measuring fluorescence parameters in multiple foci, comprises the steps of splitting a collimated primary laser beam (101) with a splitting device (102) into at least two collimated secondary laser beams (103) and deflecting the secondary laser beams such that they propagate at different propagation angles with respect to an optical axis of a focussing optic (107), focussing the secondary laser beams with the focussing optic (107) into at least two volume elements (108) in the sample, detecting light emitted from the volume elements with a detecting device (110), and evaluating the detected light for obtaining the properties to be analyzed. Furthermore, a device for implementing this method is described. The invention is particularly suited for high-throughput screening applications.
摘要:
An apparatus for illuminating a sample comprises a sample plane (205) having an illumination region onto which the sample is arranged, an excitation light unit including at least one light source (201) for generating excitation light, a lens unit having a micro lens array (206) comprising a plurality of lenses arranged in a two dimension arrangement for receiving the excitation light and generating illumination light that is directed towards the illumination region, wherein the lens unit produces homongeneous illumination light to be projected on the illumination region with a high illumination efficiency. The apparatus for illuminating may be comprised in an imaging system, said imaging system further comprising a detector for detecting signals from the sample, thereby acquiring an image, such as a fluorescence image, of the sample, focusing means for focusing the signals on the detector, and a processor for receiving data from the detector.