-
1.METHODS FOR THE TREATMENT AND DIAGNOSIS OF ALZHEIMER'S DISEASE AND TRAUMATIC BRAIN INJURIES 审中-公开
标题翻译: 方法治疗和诊断阿尔茨海默病和创伤性脑损伤公开(公告)号:EP3307392A1
公开(公告)日:2018-04-18
申请号:EP16732520.8
申请日:2016-06-10
申请人: INSERM (Institut National de la Santé et de la Recherche Médicale) , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE -CNRS- , Université Pierre et Marie Curie (Paris 6)
IPC分类号: A61P25/28 , A61K48/00 , C12N15/864 , C07K14/47
CPC分类号: C07K14/4711 , A01K2227/105 , A01K2267/0312 , A61K48/00 , A61P25/28 , C12Q1/6883 , C12Q2600/118 , C12Q2600/158 , G01N33/6896 , G01N2333/46 , G01N2800/2821
摘要: The invention relates to the use of HNRNPC-expressing vectors for preventing and/or treating a tauopathy, such as Alzheimer's disease. The invention relates to methods for detecting a risk of developing a tauopathy such Alzheimer's disease in a patient, comprising the step of detecting the level of HNRNPC in a biological sample obtained from said patient.
-
公开(公告)号:EP3297651B1
公开(公告)日:2020-02-26
申请号:EP16724409.4
申请日:2016-05-20
申请人: INSERM (Institut National de la Santé et de la Recherche Médicale) , Centre National de la Recherche Scientifique (CNRS) , Université Pierre et Marie Curie - Paris 6 (UPMC) , The Regents of the University of California , The Trustees of The University of Pennsylvania
-
3.
公开(公告)号:EP3297651A1
公开(公告)日:2018-03-28
申请号:EP16724409.4
申请日:2016-05-20
申请人: INSERM (Institut National de la Santé et de la Recherche Médicale) , Centre National de la Recherche Scientifique (CNRS) , Université Pierre et Marie Curie - Paris 6 (UPMC) , The Regents of the University of California , The Trustees of The University of Pennsylvania
发明人: LEVEILLARD, Thierry , FLANNERY, John , XIN, Mei , BYRNE, Leah , SAHEL, José-Alain , CLERIN-LACHAPELLE, Emmanuelle , JUNWEI, Sun. , BENNICELLI, Jeanette. , BENNETT, Jean.
摘要: The present invention relates to the synergistic combination of the short and long Rod-Derived Cone Viability Factors and to methods for treating retinal degenerative diseases.
-
4.TRANSGENIC RPE CELLS OVEREXPRESSING OTX2 FOR THE TREATMENT OF RETINAL DEGENERATION 审中-公开
标题翻译: 过度表达OTX2的转基因RPE细胞治疗视网膜变性公开(公告)号:EP3233093A1
公开(公告)日:2017-10-25
申请号:EP15813411.4
申请日:2015-12-17
申请人: Université Pierre et Marie Curie (Paris 6) , Centre National de la Recherche Scientifique , INSERM - Institut National de la Santé et de la Recherche Médicale
CPC分类号: A61K48/0058 , A61K35/12 , A61K48/00 , C12N5/0621 , C12N5/16 , C12N7/00 , C12N15/8645 , C12N2510/00 , C12N2750/14141
摘要: The present invention relates to methods and composition for use in the treatment of retinal degeneration, in particular retinal degeneration due to retinal pigment epithelium dysfunction.
摘要翻译: 本发明涉及用于治疗视网膜变性,特别是由于视网膜色素上皮功能障碍引起的视网膜变性的方法和组合物。
-
5.METHOD AND PHARMACEUTICAL COMPOSITION FOR USE IN THE TREATMENT OF NEURODEGENERATIVE DISORDERS 有权
标题翻译: Basigin激动剂神经退行性疾病的治疗公开(公告)号:EP2442820B1
公开(公告)日:2015-09-23
申请号:EP10727391.4
申请日:2010-06-18
申请人: INSERM - Institut National de la Santé et de la Recherche Médicale , Centre National de la Recherche Scientifique (CNRS)
CPC分类号: G01N33/5058 , A61K38/52 , G01N33/5023 , G01N2333/70596 , G01N2800/28
-
公开(公告)号:EP4366757A1
公开(公告)日:2024-05-15
申请号:EP22744718.2
申请日:2022-07-06
申请人: INSERM (Institut National de la Santé et de la Recherche Médicale) , Centre National de la Recherche Scientifique (CNRS) , Sorbonne Université
发明人: LEVEILLARD, Thierry , NOUVEL, Céline , CLERIN-LACHAPELLE, Emmanuelle , OUECHTATI, Farah , MILLET-PUEL, Géraldine
IPC分类号: A61K38/17 , A61K48/00 , A61P25/28 , C12N15/86 , C12N15/861
-
公开(公告)号:EP3570895A1
公开(公告)日:2019-11-27
申请号:EP18701288.5
申请日:2018-01-16
-
公开(公告)号:EP3548065A1
公开(公告)日:2019-10-09
申请号:EP17816576.7
申请日:2017-11-30
申请人: INSERM - Institut National de la Santé et de la Recherche Médicale , SORBONNE UNIVERSITE , Centre National de la Recherche Scientifique (CNRS)
IPC分类号: A61K38/45 , A61K48/00 , C12N15/861 , A61P27/02
-
9.
公开(公告)号:EP3307392B1
公开(公告)日:2019-05-29
申请号:EP16732520.8
申请日:2016-06-10
申请人: INSERM (Institut National de la Santé et de la Recherche Médicale) , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE -CNRS- , Sorbonne Université
IPC分类号: A61P25/28 , A61K48/00 , C12N15/864 , C07K14/47
-
公开(公告)号:EP3697448A1
公开(公告)日:2020-08-26
申请号:EP18789421.7
申请日:2018-10-22
-
-
-
-
-
-
-
-
-