摘要:
It is intended to clarify a molecule which is available as a target in treating or diagnosing cancer and utilize the molecule in the medical field or the research field. By treating IgSF4, which has been identified as a molecule specifically expressed in lung cancer cells, with an antibody, an ADCC activity is exerted. Based on this finding, an anti-IgSF4 antibody is provided as a means efficacious in treating cancer, etc.
摘要:
An affinitive linker is introduced into a target substance and captured by a binding partner capable of binding to the affinitive linker to thereby select a binding molecule capable of binding to the target substance. For example, a sugar chain contained in an influenza virus antigen is labeled with an affinitive linker such as biotin and allowed to bind to streptpavidin serving as a binding partner and then recovered. Thus, an antibody binding to the antigen can be easily concentrated. This method of selecting a binding molecule is useful in screening a neutralizer.