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公开(公告)号：EP2805947A4
公开(公告)日：2015-05-27
申请号：EP13738361
申请日：2013-01-15
发明人： LI SONG , WANG YING , XIAO JUNHAI , MA DALONG , GONG HONGWEI , QI HUI , WANG LILI , LING XIAOMEI , ZHENG ZHIBING , ZHANG YANG , ZHONG WU , LI MEINA , XIE YUNDE , XU ENQUAN , LI XINGZHOU , MA JING , ZHAO GUOMING , ZHOU XINBO , WANG XIAOKUI , LIU HONGYING
IPC分类号： C07D403/14 , A61K31/506 , A61K31/519 , A61P11/06 , A61P17/00 , A61P29/00 , A61P37/00 , C07D239/50 , C07D403/12 , C07D417/12
CPC分类号： C07D471/04 , C07D239/50 , C07D401/12 , C07D403/12 , C07D403/14 , C07D417/12
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公开(公告)号：EP2005945A4
公开(公告)日：2012-12-19
申请号：EP06775361
申请日：2006-08-11
发明人： LI SONG , ZHONG WU , XIAO JUNHAI , XIE YUNDE , LI XINGZHOU , CUI HAO , ZHENG ZHIBING
IPC分类号： A61K9/16 , A61K31/215 , A61P31/12
CPC分类号： A61K31/215 , A61K9/0056 , A61K9/0095 , A61K9/141 , A61K9/1623 , A61K9/1635 , A61K9/1652
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3.发明公开
公开(公告)号：EP2447253A4
公开(公告)日：2012-11-14
申请号：EP10791138
申请日：2010-05-27
发明人： LI SONG , XU XIAOQIAN , ZHAO GUOMING , WANG LILI , GUAN HUA , XIAO JUNHAI , ZHONG WU , ZHENG ZHIBING , XIE YUNDE , LI XINGZHOU , WANG XIAOKUI , ZHOU XINBO , LIU HONGYING
IPC分类号： C07D239/20 , A61K31/505 , A61K31/506 , A61P31/12 , C07D401/06 , C07D401/14 , C07D403/06
CPC分类号： C07D239/20 , A61K31/4025 , A61K31/4453 , A61K31/505 , A61K31/506 , A61K45/06 , C07D211/14 , C07D239/28 , C07D239/557 , C07D401/06 , C07D403/06 , A61K2300/00
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4.发明公开
公开(公告)号：EP2573067A4
公开(公告)日：2014-10-29
申请号：EP11782849
申请日：2011-05-16
发明人： LI SONG , ZHONG WU , LIU PING , XIAO JUNHAI , ZHENG ZHIBING , XIE YUNDE , ZHAO GUOMING , WANG XIAOKUI , WANG LILI , LI XINGZHOU , ZHOU XINBO
IPC分类号： C07C215/62 , A61K31/137 , A61P31/06 , C07C217/72
CPC分类号： C07C217/72 , A61K31/137 , C07C213/00 , C07C215/62
摘要： The present invention relates to aromatic butan-2-ol compounds and preparation methods and uses thereof. Specifically, the present invention relates to the compound of Formula I, or an optical isomer, racemate, diastereomer, pharmaceutically acceptable salt or solvate thereof: wherein each of the substituents have the definitions as given in the specification. The present invention further relates to a pharmaceutical composition containing the compound, and the use of the compound in manufacture of a medicament for the treatment and/or prophylaxis of a disease or disorder caused by tubercle bacillus infection. The compound of Formula I of the present invention has advantages in treatment and/or prophylaxis of a disease or disorder caused by tubercle bacillus infection.
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5.发明公开2,4,5-TRISUBSTITUTED THIAZOLE COMPOUNDS,PREPARATION METHODS, PHARMACEUTICAL COMPOSITIONS AND MEDICAL USES THEREOF 有权2,4,5-三取代的噻唑，方法，药物组合物和医疗应用THEREOF
公开(公告)号：EP2042494A4
公开(公告)日：2011-06-29
申请号：EP06775389
申请日：2006-08-15
发明人： LI SONG , GUO CHANGBIN , JIANG XIANCHENG , XIAO JUNHAI , ZHONG WU
IPC分类号： C07D277/46 , A61K31/426 , A61P7/00 , A61P9/00 , A61P9/10 , C07D277/40 , C07D277/44 , C07D417/04
CPC分类号： C07D277/40 , C07D277/24 , C07D277/42 , C07D277/44 , C07D277/46 , C07D277/50 , C07D277/52
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6.发明公开
公开(公告)号：EP2955174A4
公开(公告)日：2016-09-28
申请号：EP13874809
申请日：2013-12-10
发明人： LI SONG , XIAO JUNHAI , ZHAO MINGMING , ZHONG WU , WANG LILI , ZHENG ZHIBING , XIE YUNDE , LI XINGZHOU , ZHAO GUOMING , ZHOU XINBO , WANG XIAOKUI , CHEN WEI
IPC分类号： C07D307/33 , A61K31/635 , A61P31/04
CPC分类号： C07D307/33 , A61K31/365 , A61K45/06
摘要： Disclosed are a derivative of homoserine lactone represented by formula I, and a preparation method and use thereof. The compound has a bacterial quorum-sensing regulatory effect, and can be used for prevention and/or treatment of a disease caused by a bacterial infection.
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公开(公告)号：EP2952509A4
公开(公告)日：2016-06-22
申请号：EP13874396
申请日：2013-12-10
发明人： LI SONG , XIAO JUNHAI , ZHAO MINGMING , ZHONG WU , WANG LILI , ZHENG ZHIBING , XIE YUNDE , LI XINGZHOU , ZHAO GUOMING , ZHOU XINBO , WANG XIAOKUI , CHEN WEI
IPC分类号： C07D263/26 , A61K31/421 , A61P31/04
CPC分类号： C07D263/26 , A61K31/421 , A61K45/06
摘要： The invention relates to a compound of formula I, and a preparation method and use thereof. The compound has a bacterial quorum-sensing regulatory effect, and can be used for prevention and/or treatment of a disease caused by a bacterial infection.
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8.发明公开(1S, 2S, 3S, 4R)-3-Ý(1S)-1-ACETYLAMINO-2-ETHYL-BUTYL¨-4-GUANIDINO-2- HYDROXYL-CYCLOPENTYL-1-CARBOXYLIC ACID HYDRATES AND PHARMACEUTICAL USES THEREOF 审中-公开（1S，2S，3S，4R）-3 - [（1S）-1-乙酰氨基-2-乙基 - 丁基] -4-胍基-2-羟基 - 环戊烯-1-碳酸钠在IHRE PHARMAZEUCHSCHE VERWENDUNG
公开(公告)号：EP2186795A4
公开(公告)日：2014-05-07
申请号：EP08800493
申请日：2008-08-13
发明人： LI SONG , ZHONG WU , ZHENG ZHIBING , ZHOU XINBO , XIAO JUNHAI , XIE YUNDE , WANG LILI , LI XINGZHOU , ZHAO GUOMING , WANG XIAOKUI , LIU HONGYING
IPC分类号： C07C279/16 , A61K31/155 , A61P11/00 , A61P31/12
CPC分类号： C07C279/16 , C07B2200/07 , C07C277/06 , C07C277/08 , C07C2601/08
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9.发明公开
公开(公告)号：EP3006432A4
公开(公告)日：2016-10-26
申请号：EP14804849
申请日：2014-05-28
发明人： LI SONG , XIAO JUNHAI , ZHANG XIAN , ZHONG WU , ZHENG ZHIBING , WANG LILI , XIE YUNDE , LI XINGZHOU , ZHOU XINBO , WANG XIAOKUI
IPC分类号： C07D303/48 , A61K31/336 , A61K31/427 , A61K31/428 , A61P31/14 , A61P31/16 , C07D301/00 , C07D417/12 , C07D417/14
CPC分类号： C07D417/12 , C07D303/48 , C07D417/14
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10.发明公开THIAZINE AMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION AND USE THEREOF 有权THIAZINAMIDDERIVAT和药物组合物及其用途
公开(公告)号：EP2889293A4
公开(公告)日：2015-12-30
申请号：EP12883262
申请日：2012-08-24
发明人： LI SONG , XIAO JUNHAI , HAN DAN , ZHONG WU , WANG LILI , ZHENG ZHIBING , XIE YUNDE , ZHOU XINBO , LI XINGZHOU , WANG XIAOKUI , JIANG DAN , CHEN WEI , LIU HONGYING
CPC分类号： C07D279/12
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