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公开(公告)号：EP2805947A4
公开(公告)日：2015-05-27
申请号：EP13738361
申请日：2013-01-15
发明人： LI SONG , WANG YING , XIAO JUNHAI , MA DALONG , GONG HONGWEI , QI HUI , WANG LILI , LING XIAOMEI , ZHENG ZHIBING , ZHANG YANG , ZHONG WU , LI MEINA , XIE YUNDE , XU ENQUAN , LI XINGZHOU , MA JING , ZHAO GUOMING , ZHOU XINBO , WANG XIAOKUI , LIU HONGYING
IPC分类号： C07D403/14 , A61K31/506 , A61K31/519 , A61P11/06 , A61P17/00 , A61P29/00 , A61P37/00 , C07D239/50 , C07D403/12 , C07D417/12
CPC分类号： C07D471/04 , C07D239/50 , C07D401/12 , C07D403/12 , C07D403/14 , C07D417/12
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2.发明公开
公开(公告)号：EP2447253A4
公开(公告)日：2012-11-14
申请号：EP10791138
申请日：2010-05-27
发明人： LI SONG , XU XIAOQIAN , ZHAO GUOMING , WANG LILI , GUAN HUA , XIAO JUNHAI , ZHONG WU , ZHENG ZHIBING , XIE YUNDE , LI XINGZHOU , WANG XIAOKUI , ZHOU XINBO , LIU HONGYING
IPC分类号： C07D239/20 , A61K31/505 , A61K31/506 , A61P31/12 , C07D401/06 , C07D401/14 , C07D403/06
CPC分类号： C07D239/20 , A61K31/4025 , A61K31/4453 , A61K31/505 , A61K31/506 , A61K45/06 , C07D211/14 , C07D239/28 , C07D239/557 , C07D401/06 , C07D403/06 , A61K2300/00
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3.发明公开
公开(公告)号：EP2955174A4
公开(公告)日：2016-09-28
申请号：EP13874809
申请日：2013-12-10
发明人： LI SONG , XIAO JUNHAI , ZHAO MINGMING , ZHONG WU , WANG LILI , ZHENG ZHIBING , XIE YUNDE , LI XINGZHOU , ZHAO GUOMING , ZHOU XINBO , WANG XIAOKUI , CHEN WEI
IPC分类号： C07D307/33 , A61K31/635 , A61P31/04
CPC分类号： C07D307/33 , A61K31/365 , A61K45/06
摘要： Disclosed are a derivative of homoserine lactone represented by formula I, and a preparation method and use thereof. The compound has a bacterial quorum-sensing regulatory effect, and can be used for prevention and/or treatment of a disease caused by a bacterial infection.
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公开(公告)号：EP2952509A4
公开(公告)日：2016-06-22
申请号：EP13874396
申请日：2013-12-10
发明人： LI SONG , XIAO JUNHAI , ZHAO MINGMING , ZHONG WU , WANG LILI , ZHENG ZHIBING , XIE YUNDE , LI XINGZHOU , ZHAO GUOMING , ZHOU XINBO , WANG XIAOKUI , CHEN WEI
IPC分类号： C07D263/26 , A61K31/421 , A61P31/04
CPC分类号： C07D263/26 , A61K31/421 , A61K45/06
摘要： The invention relates to a compound of formula I, and a preparation method and use thereof. The compound has a bacterial quorum-sensing regulatory effect, and can be used for prevention and/or treatment of a disease caused by a bacterial infection.
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5.发明公开(1S, 2S, 3S, 4R)-3-Ý(1S)-1-ACETYLAMINO-2-ETHYL-BUTYL¨-4-GUANIDINO-2- HYDROXYL-CYCLOPENTYL-1-CARBOXYLIC ACID HYDRATES AND PHARMACEUTICAL USES THEREOF 审中-公开（1S，2S，3S，4R）-3 - [（1S）-1-乙酰氨基-2-乙基 - 丁基] -4-胍基-2-羟基 - 环戊烯-1-碳酸钠在IHRE PHARMAZEUCHSCHE VERWENDUNG
公开(公告)号：EP2186795A4
公开(公告)日：2014-05-07
申请号：EP08800493
申请日：2008-08-13
发明人： LI SONG , ZHONG WU , ZHENG ZHIBING , ZHOU XINBO , XIAO JUNHAI , XIE YUNDE , WANG LILI , LI XINGZHOU , ZHAO GUOMING , WANG XIAOKUI , LIU HONGYING
IPC分类号： C07C279/16 , A61K31/155 , A61P11/00 , A61P31/12
CPC分类号： C07C279/16 , C07B2200/07 , C07C277/06 , C07C277/08 , C07C2601/08
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公开(公告)号：EP3006431A4
公开(公告)日：2016-11-02
申请号：EP14820360
申请日：2014-07-04
发明人： LI SONG , LI XINGZHOU , ZHONG WU , ZHENG ZHIBING , XIAO JUNHAI , ZHOU XINBO , XIE YUNDE , WANG XIAOKUI , WANG LILI , CHEN WEI , XIE FEI
IPC分类号： C07D277/58 , A61K31/426 , A61K31/4439 , A61K31/454 , A61K31/496 , A61K31/5377 , A61K31/675 , A61P31/04 , A61P31/14 , A61P31/16 , A61P31/20 , A61P33/02 , A61P33/10 , C07D417/12 , C07F9/6539
CPC分类号： C07D277/58 , C07D401/12 , C07D417/12
摘要： The invention relates to a tizoxanide carbamate compound of Formula I and a pharmaceutically acceptable salt, a hydrate or a solvate thereof, and their pharmaceutical use.
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7.发明公开PYRIDAZINE DERIVATIVES AND USE THEREOF AS MEDICAMENTS FOR TREATING MICRORNA VIRAL INFECTION 有权哒嗪和它们作为药物的微RNA病毒感染的治疗
公开(公告)号：EP2602252A4
公开(公告)日：2014-01-01
申请号：EP11814093
申请日：2011-08-02
发明人： LI SONG , WANG HONGLIANG , XIAO JUNHAI , ZHANG XIAN , WANG LILI , ZHENG ZHIBING , ZHONG WU , XIE YUNDE , LI XINGZHOU , ZHOU XINBO , ZHAO GUOMING , WANG XIAOKUI
IPC分类号： C07D401/04 , A61K31/501 , A61P31/16
CPC分类号： C07D237/20
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8.发明公开
公开(公告)号：EP3006432A4
公开(公告)日：2016-10-26
申请号：EP14804849
申请日：2014-05-28
发明人： LI SONG , XIAO JUNHAI , ZHANG XIAN , ZHONG WU , ZHENG ZHIBING , WANG LILI , XIE YUNDE , LI XINGZHOU , ZHOU XINBO , WANG XIAOKUI
IPC分类号： C07D303/48 , A61K31/336 , A61K31/427 , A61K31/428 , A61P31/14 , A61P31/16 , C07D301/00 , C07D417/12 , C07D417/14
CPC分类号： C07D417/12 , C07D303/48 , C07D417/14
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9.发明公开THIAZINE AMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION AND USE THEREOF 有权THIAZINAMIDDERIVAT和药物组合物及其用途
公开(公告)号：EP2889293A4
公开(公告)日：2015-12-30
申请号：EP12883262
申请日：2012-08-24
发明人： LI SONG , XIAO JUNHAI , HAN DAN , ZHONG WU , WANG LILI , ZHENG ZHIBING , XIE YUNDE , ZHOU XINBO , LI XINGZHOU , WANG XIAOKUI , JIANG DAN , CHEN WEI , LIU HONGYING
CPC分类号： C07D279/12
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10.发明公开THIAZOLAMINE DERIVATIVE AND USE THEREOF AS ANTI-PICORNAVIRAL INFECTION MEDICAMENT 有权THIAZOLAMINDERIVAT及其作为药物的用途反对小核糖核酸病毒感染
公开(公告)号：EP2650292A4
公开(公告)日：2014-05-07
申请号：EP11847007
申请日：2011-12-06
发明人： LI SONG , WANG HONGLIANG , XIAO JUNHAI , ZHANG XIAN , WANG LILI , ZHENG ZHIBING , ZHONG WU , XIE YUNDE , LI XINGZHOU , ZHOU XINBO , ZHAO GUOMING , WANG XIAOKUI
IPC分类号： C07D417/04 , A61K31/496 , A61P31/14 , A61P31/16
CPC分类号： C07D417/04 , A61K31/496 , C07D277/42
摘要： Disclosed is as a substituted thiazolamine derivative represented by Formula I or a pharmaceutically acceptable salt thereof or a hydrate thereof (the definitions of each group in the formula are as presented in the description), and the application thereof in the prevention and/or treatment of viral diseases induced by picornavirus. Also disclosed is a pharmaceutical composition containing the compound.
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