摘要:
The invention relates to an arrangement for the production, testing and archiving of chemical or biological arrays bonded to a solid phase. The aim of the invention is to define such an arrangement which guarantees a locally-defined, temporary binding of individual solid phase supports to a common base support and simultaneously permits a transformation of the individual solid phase supports, according to a protocol, whereby any complete combined array or a subset thereof can be generated. Said aim is achieved, whereby a base support is formed from a large-surface support plate with a planar or arched surface form. Said base support (2) is provided with a number of discrete regions of elevated magnetic field strength, each of which permits a detachable attachment and retention of a solid phase support (1), each comprising a corresponding magnetic or magnetisable element (11), associated with a region of elevated magnetic field strength, such as a magnetic element (21) on the base support (2). The curvature of the surface of the solid phase support (1), facing the base support surface, matches the curvature of the base support surface to give a flush fit and the solid phase support (1) facing away from the base support surface (2) is provided with a functional layer (12) for the permanent bonding of chemical or biological substances.
摘要:
The invention relates to a magnetic handling device for objects which are arranged in a matrix-type manner. The aim of the invention is to provide a magnetic handling device which is able to pick up and transport small and extremely small ferromagnetic objects which are arranged in a matrix without affecting the positions of said objects relative to each other. To this end, the magnet poles are arranged in a matrix above and/or below the objects to be handled, in the direction of handling. The invention also relates to a magnetic handling device for handling ferromagnetic objects which are arranged in a matrix, especially particles which serve as supports for chemical samples, said handling device having several magnet poles.
摘要:
The invention relates to a magnetic grip/hold system for handling magnetic objects that are arranged in a matrix, especially for handling particles that carry chemically samples. At least one part of the magnetic objects can be simultaneously displaced to a new position without changing its association with the matrix by producing a magnetic force that partially acts upon to the matrix. The aim of the invention is to provide a system that is economic in operation and that prevents the formation of global local interference of magnetic fields as well as the reduction of useful magnetic force. To this end, every magnetic object is associated with a holding magnetic field that is overlayered by a movable gripping magnetic field that partially acts upon the matrix.
摘要:
The invention relates to an arrangement for the production, testing and archiving of chemical or biological arrays bonded to a solid phase. The aim of the invention is to define such an arrangement which guarantees a locally-defined, temporary binding of individual solid phase supports to a common base support and simultaneously permits a transformation of the individual solid phase supports, according to a protocol, whereby any complete combined array or a subset thereof can be generated. Said aim is achieved, whereby a base support is formed from a large-surface support plate with a planar or arched surface form. Said base support (2) is provided with a number of discrete regions of elevated magnetic field strength, each of which permits a detachable attachment and retention of a solid phase support (1), each comprising a corresponding magnetic or magnetisable element (11), associated with a region of elevated magnetic field strength, such as a magnetic element (21) on the base support (2). The curvature of the surface of the solid phase support (1), facing the base support surface, matches the curvature of the base support surface to give a flush fit and the solid phase support (1) facing away from the base support surface (2) is provided with a functional layer (12) for the permanent bonding of chemical or biological substances.