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1.发明授权GLYCOCONJUGATES AND THEIR USE AS POTENTIAL VACCINES AGAINST INFECTION BY SHIGELLA FLEXNERI 有权糖复合物及其作为候选疫苗抗感染与志贺菌
公开(公告)号：EP1642132B1
公开(公告)日：2011-06-22
申请号：EP04744281.9
申请日：2004-07-02
申请人： INSTITUT PASTEUR , INSERM (Institut National de la Santé et de la Recherche Médicale) , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
发明人： PHALIPON, Armelle , NATO, Farida , MULARD, Laurence , SANSONETTI, Philippe , GRANDJEAN, Cyrille , BALEUX, Francoise , BELOT, Frédéric
IPC分类号： G01N33/569 , C07K16/12 , A61K47/48 , C07H3/06 , G01N33/563 , A61K39/112
CPC分类号： A61K39/0283 , A61K47/557 , A61K47/61 , A61K47/6415 , A61K47/646 , A61K2039/6031 , A61K2039/6037 , A61K2039/625 , C07H3/06 , C07K16/1228 , C07K2317/565 , C08B37/006 , G01N33/563 , G01N33/56916 , Y02A50/476
摘要： The present invention relates to a saccharide selected from the group consisting of: €ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ{B(E)CD} €ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ{(E)CDAB}n €ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ{AB(E)CD}n Wherein A, B, C, E, D and n are as defined in claim 1. The invention also relates to derivatives thereof, pharmaceutical compositions comprising said derivatives, and kit for the diagnostic of Shigella flexneri type 2a infection comprising said derivatives.
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2.发明公开UTILISATION DES ACIDES QUINIQUE, SHIKIMIQUE ET DE LEURS DERIVES POUR LA PREPARATION DE LIGANDS DU RECEPTEUR DU MANNOSE 审中-公开中国和莽草酸及其衍生物为配体甘露糖受体的制备中使用
公开(公告)号：EP1200462A2
公开(公告)日：2002-05-02
申请号：EP00956573.0
申请日：2000-07-28
发明人： GRANDJEAN, Cyrille , MELNYK, Oleg , GRAS-MASSE, Hélène , ANGYALOSI, Gerhild , ROMMENS, Corinne , AURIAULT, Claude
IPC分类号： C07K14/00 , C07K7/02 , C07K5/023 , C07K5/037 , A61K38/04 , A61K38/16 , G01N33/68 , A61K31/19
CPC分类号： C07K5/0202 , C07K5/0215 , C07K7/02 , C07K14/001
摘要： The invention concerns the use of quinic, shimic acids and their derivatives for preparing mannose receptor ligands, the resulting ligands and the uses of said ligands, in particular for preparing medicines and, more particularly for preparing vaccines and medicines for vectoring an active principle to target cells expressing the mannose receptor or a receptor related thereto, for transfecting DNA and RNA sequences and numerous other uses in gene therapy, and for preparing laboratory reagents, in particular diagnostic reagents.
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3.发明公开GLYCOCONJUGATES AND THEIR USE AS POTENTIAL VACCINES AGAINST INFECTION BY SHIGELLA FLEXNERI 有权糖复合物及其作为候选疫苗抗感染与志贺菌
公开(公告)号：EP1642132A2
公开(公告)日：2006-04-05
申请号：EP04744281.9
申请日：2004-07-02
申请人： INSTITUT PASTEUR , INSERM (Institut National de la Santé et de la Recherche Medicale) , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
发明人： PHALIPON, Armelle , NATO, Farida , MULARD, Laurence , SANSONETTI, Philippe , GRANDJEAN, Cyrille , BALEUX, Francoise , BELOT, Frédéric
IPC分类号： G01N33/569 , C07K16/12 , A61K47/48 , C07H3/06 , G01N33/563 , A61K39/112
CPC分类号： A61K39/0283 , A61K47/557 , A61K47/61 , A61K47/6415 , A61K47/646 , A61K2039/6031 , A61K2039/6037 , A61K2039/625 , C07H3/06 , C07K16/1228 , C07K2317/565 , C08B37/006 , G01N33/563 , G01N33/56916 , Y02A50/476
摘要： The present invention relates to a saccharide selected from the group consisting of: €ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ{B(E)CD} €ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ{(E)CDAB}n €ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ{AB(E)CD}n Wherein A, B, C, E, D and n are as defined in claim 1. The invention also relates to derivatives thereof, pharmaceutical compositions comprising said derivatives, and kit for the diagnostic of Shigella flexneri type 2a infection comprising said derivatives.
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