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1.发明授权LIPOSOMES, ET LEUR UTILISATION NOTAMMENT POUR L'OBTENTION DE COMPOSITIONS IMMUNOMODULATRICES 失效脂质体及其用途，特别用于制造免疫调节介质
公开(公告)号：EP0748214B1
公开(公告)日：1998-10-07
申请号：EP95910590.9
申请日：1995-02-23
申请人： INSTITUT PASTEUR , INSTITUT PASTEUR DE LILLE , INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)
IPC分类号： A61K9/127
CPC分类号： A61K39/39 , A61K9/127 , A61K39/0003 , A61K2039/543 , A61K2039/55555 , Y02A50/423
摘要： The liposomes of the invention comprise at least one dual layer comprising a mixture formed by a phospholipid (I) with a flow temperature of 20-25 DEG C, and a phospholipid (II) with a flow temperature of 20-60 DEG C. The invention is characterized in that the molar ratio of phospholipid (I) to phospholipid (II) is 5:95 - 30:70. Said liposomes are for use in the production of vaccines.
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2.发明公开LIPOSOMES, ET LEUR UTILISATION NOTAMMENT POUR L'OBTENTION DE COMPOSITIONS IMMUNOMODULATRICES 失效脂质体及其用途，特别用于制造免疫调节介质
公开(公告)号：EP0748214A1
公开(公告)日：1996-12-18
申请号：EP95910590.0
申请日：1995-02-23
申请人： INSTITUT PASTEUR , INSTITUT PASTEUR DE LILLE , INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)
CPC分类号： A61K39/39 , A61K9/127 , A61K39/0003 , A61K2039/543 , A61K2039/55555 , Y02A50/423
摘要： The liposomes of the invention comprise at least one dual layer comprising a mixture formed by a phospholipid (I) with a flow temperature of 20-25 °C, and a phospholipid (II) with a flow temperature of 20-60 °C. The invention is characterized in that the molar ratio of phospholipid (I) to phospholipid (II) is 5:95 - 30:70. Said liposomes are for use in the production of vaccines.
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