专利检索 ap:("INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES") AND inv:"LIN, Songwen" 第 1 页

1.

发明公开
QUINAZOLINE COMPOUND AND PREPARATION METHOD, APPLICATION, AND PHARMACEUTICAL COMPOSTION THEREOF 审中-公开

公开(公告)号：EP4169917A1

公开(公告)日：2023-04-26

申请号：EP22213583.2

申请日：2017-12-26

申请人： Institute of Materia Medica, Chinese Academy of Medical Sciences

发明人： XU, Heng , CHEN, Xiaoguang , LIN, Songwen , JI, Ming , JIN, Jing , WU, Deyu , WANG, Yangchun , LV, Yuanhao

IPC分类号： C07D405/14 , C07D401/14 , C07D401/04 , A61K31/517 , A61K31/5377

摘要： The invention relates to quinazoline compounds, the preparation method, use, and the pharmaceutical composition thereof. The said quinazoline compounds, which are represented by Formula (I), are phosphatidylinositol 3-kinase (PI3K) inhibitors, and can be applied to prevent and/or treat PI3K activity-related diseases, such as cancer, immune diseases, cardiovascular diseases, viral infections, inflammation, metabolism/endocrine function disorders or neurological diseases.

2.

发明公开
QUINAZOLINE COMPOUND AND PREPARATION METHOD, APPLICATION, AND PHARMACEUTICAL COMPOSTION THEREOF 审中-公开

公开(公告)号：EP4169918A1

公开(公告)日：2023-04-26

申请号：EP22213594.9

申请日：2017-12-26

申请人： Institute of Materia Medica, Chinese Academy of Medical Sciences

发明人： XU, Heng , CHEN, Xiaoguang , LIN, Songwen , JI, Ming , JIN, Jing , WU, Deyu , WANG, Yangchun , LV, Yuanhao

IPC分类号： C07D405/14 , C07D401/14 , C07D401/04 , C07D409/14 , A61K31/517 , A61K31/5377

摘要： The invention relates to quinazoline compounds, the preparation method, use, and the pharmaceutical composition thereof. The said quinazoline compounds, which are represented by Formula (I), are phosphatidylinositol 3-kinase (PI3K) inhibitors, and can be applied to prevent and/or treat PI3K activity-related diseases, such as cancer, immune diseases, cardiovascular diseases, viral infections, inflammation, metabolism/endocrine function disorders or neurological diseases.

3.

发明公开
QUINAZOLINE COMPOUND AND PREPARATION METHOD, APPLICATION, AND PHARMACEUTICAL COMPOSTION THEREOF 审中-公开

公开(公告)号：EP3560921A1

公开(公告)日：2019-10-30

申请号：EP17886474.0

申请日：2017-12-26

申请人： INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES

发明人： XU, Heng , CHEN, Xiaoguang , LIN, Songwen , JI, Ming , JIN, Jing , WU, Deyu , WANG, Yangchun , LV, Yuanhao

IPC分类号： C07D405/14 , C07D401/14 , C07D401/04 , A61K31/517 , A61K31/5377

摘要： The invention relates to quinazoline compounds, the preparation method, use, and the pharmaceutical composition thereof. The said quinazoline compounds, which are represented by Formula (I), are phosphatidylinositol 3-kinase (PI3K) inhibitors, and can be applied to prevent and/or treat PI3K activity-related diseases, such as cancer, immune diseases, cardiovascular diseases, viral infections, inflammation, metabolism/endocrine function disorders or neurological diseases.