专利检索 ap:("ISIS PHARMACEUTICALS, INC." OR "NATIONAL UNIVERSITY OF SINGAPORE") AND inv:"WONG, Wai Shiu Fred" 第 1 页

1.

发明公开
ANTISENSE MODULATION OF p38 MITOGEN ACTIVATED PROTEIN KINASE EXPRESSION 有权
标题翻译：丝裂原活化蛋白激酶的表达的p38反义调节

公开(公告)号：EP1660682A2

公开(公告)日：2006-05-31

申请号：EP04781089.0

申请日：2004-08-12

申请人： ISIS PHARMACEUTICALS, INC. , NATIONAL UNIVERSITY OF SINGAPORE

发明人： MONIA, Brett P. , DOBIE, Kenneth W. , FREIER, Susan M. , POPOFF, Ian , WONG, Wai Shiu Fred , KARRAS, James G.

IPC分类号： C12Q1/68 , A01N43/04 , C07H21/04 , A61K31/07

CPC分类号： C12N15/1137 , A61K31/7052 , A61K38/00 , C12N2310/11 , C12N2310/14 , C12N2310/315 , C12N2310/321 , C12N2310/3341 , C12N2310/341 , C12N2310/346 , C12Y207/11024 , Y02P20/582 , C12N2310/3525

摘要： Compositions and methods for the treatment and diagnosis of diseases or conditions amenable to treatment through modulation of expression of a gene encoding a p38 mitogen-activated protein kinase (p38 MAPK) are provided. Methods for decreasing airway hyperresponsiveness or airway inflammation in an animal are also provided.

2.

发明授权
ANTISENSE MODULATION OF p38 MITOGEN ACTIVATED PROTEIN KINASE EXPRESSION 有权
标题翻译：丝裂原活化蛋白激酶的表达的p38反义调节

公开(公告)号：EP1660682B1

公开(公告)日：2011-10-05

申请号：EP04781089.0

申请日：2004-08-12

申请人： Isis Pharmaceuticals, Inc. , NATIONAL UNIVERSITY OF SINGAPORE

发明人： MONIA, Brett P. , DOBIE, Kenneth W. , FREIER, Susan M. , POPOFF, Ian , WONG, Wai Shiu Fred , KARRAS, James G.

IPC分类号： C12Q1/68 , A01N43/04 , C07H21/04 , A61K31/07

CPC分类号： C12N15/1137 , A61K31/7052 , A61K38/00 , C12N2310/11 , C12N2310/14 , C12N2310/315 , C12N2310/321 , C12N2310/3341 , C12N2310/341 , C12N2310/346 , C12Y207/11024 , Y02P20/582 , C12N2310/3525

摘要： Compositions and methods for the treatment and diagnosis of diseases or conditions amenable to treatment through modulation of expression of a gene encoding a p38 mitogen-activated protein kinase (p38 MAPK) are provided. Methods for decreasing airway hyperresponsiveness or airway inflammation in an animal are also provided.