专利检索 ap:("ISRAEL INSTITUTE FOR BIOLOGICAL RESEARCH" OR "Life Science Research Israel Ltd.") AND inv:"ADANI, Rachel" 第 1 页

1.

发明公开
COMPOUNDS CO-INDUCING CHOLINERGIC UP-REGULATION AND INFLAMMATION DOWN-REGULATION AND USES THEREOF 审中-公开
标题翻译：化合物胆碱能上调，炎性下调及其应用的复合诱导

公开(公告)号：EP1385824A2

公开(公告)日：2004-02-04

申请号：EP02712224.1

申请日：2002-02-17

申请人： ISRAEL INSTITUTE FOR BIOLOGICAL RESEARCH , Life Science Research Israel Ltd.

发明人： AMITAI, Gabriel , ADANI, Rachel , RABINOVITZ, Ishai , SOD-MORIAH, Gali , MESHULAM, Haim

IPC分类号： C07D211/60

CPC分类号： A61K31/4425 , A61K31/405 , A61K31/439 , A61K31/4439 , A61K31/455

摘要： Chimeric compounds are disclosed which are covalent conjugates of reversible or irreversible cholinergic up-regulators and non-steroidal anti-inflammatory drugs (NSAIDs), methods for their synthesis and use thereof for treatment and/or prevention of central nervous system (CNS) disorders and diseases.