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公开(公告)号：EP3229779A1
公开(公告)日：2017-10-18
申请号：EP15820375.2
申请日：2015-12-10
申请人： Incept, LLC
CPC分类号： A61K9/0051 , A61K9/50 , A61K39/3955 , A61K47/10
摘要： Materials and methods for treating a patient, optionally a patient with an eye disease, comprising providing a collection of particles that comprise a first biodegradable material that is a hydrogel or a xerogel and a therapeutic agent, with the first material, before biodegradation, having a rate of release for the therapeutic agent as measured in physiological solution, and forming a second hydrogel
ex vivo or
in situ on a tissue of the patient at a site of intended use, optionally at or near an eye, that at least partially coats the collection of particles. The agent is released to treat the patient.摘要翻译： 用于治疗患者，任选地患有眼病的患者的材料和方法，包括提供一组颗粒，所述颗粒包含作为水凝胶或干凝胶的第一可生物降解材料和治疗剂，其中所述第一材料在生物降解之前具有 在生理溶液中测量的治疗剂的释放速率，以及在预期使用位置处，在任选地在眼睛处或附近的患者组织上离体或原位形成第二水凝胶，所述第二水凝胶至少部分地涂覆所述收集物 的颗粒。 代理商被释放以治疗病人。
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公开(公告)号：EP3965668A1
公开(公告)日：2022-03-16
申请号：EP20806304.0
申请日：2020-05-08
申请人： Incept, LLC
IPC分类号： A61B17/12
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公开(公告)号：EP3583960A1
公开(公告)日：2019-12-25
申请号：EP19185126.0
申请日：2010-12-15
申请人： Incept, LLC
IPC分类号： A61L27/50 , A61L31/12 , A61L27/58 , A61L27/14 , A61L27/54 , A61L31/18 , A61L31/14 , A61L27/52
摘要： Implantable materials may be used in an iatrogenic site. Applications include radioopaque materials for fiducial marking.
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公开(公告)号：EP3960215A1
公开(公告)日：2022-03-02
申请号：EP21203718.8
申请日：2010-12-15
申请人： Incept, LLC
IPC分类号： A61L27/50 , A61L31/12 , A61L27/58 , A61L27/14 , A61L27/54 , A61L27/52 , A61L31/14 , A61L31/18 , A61P15/00 , A61P35/00 , A61P43/00
摘要： Implantable materials may be used in an iatrogenic site. Applications include radioopaque materials for fiducial marking.
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公开(公告)号：EP3153194A1
公开(公告)日：2017-04-12
申请号：EP16199383.7
申请日：2010-05-04
申请人： Incept, LLC
CPC分类号： A61B17/0057 , A61B2017/00004 , A61B2017/00557 , A61B2017/0065 , A61B2017/00654 , A61L31/06 , A61L31/145 , A61L31/148
摘要： Embodiments include coatings for adherence of biomaterials to a tissue. Systems and methods for adapting such coated materials to vascular access closure are further proved.
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公开(公告)号：EP3858329A1
公开(公告)日：2021-08-04
申请号：EP20214440.8
申请日：2015-12-10
申请人： Incept, LLC
摘要： Materials and methods for treating a patient, optionally a patient with an eye disease, comprising providing a collection of particles that comprise a first biodegradable material that is a hydrogel or a xerogel and a therapeutic agent, with the first material, before biodegradation, having a rate of release for the therapeutic agent as measured in physiological solution, and forming a second hydrogel ex vivo or in situ on a tissue of the patient at a site of intended use, optionally at or near an eye, that at least partially coats the collection of particles. The agent is released to treat the patient.
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公开(公告)号：EP4197527A1
公开(公告)日：2023-06-21
申请号：EP23154758.9
申请日：2017-09-25
申请人： Incept, LLC
发明人： SAWHNEY, Amarpreet S. , DRISCOLL, Arthur , BLIZZARD, Charles D. , DESAI, Ankita Darshan , JARRETT, Peter
摘要： Methods of treating an eye for an ocular condition such as placing a composite depot comprising a xerogel with embedded degradable particles into an anterior chamber of an eye to deliver a therapeutic agent. The xerogel is a hydrogel after exposure to intraocular fluid and is degradable. The degradable particles comprise the therapeutic agent and hydrolytically degrade in the anterior chamber to provide a controlled release of the therapeutic agent into the eye. Materials and processes for making depots are provided as well as alternative methods of their use.
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